Functional inactivation of pulmonary MAIT cells following 5-OP-RU treatment of non-human primates

Targeting MAIT cells holds promise for the treatment of different diseases and infections. We previously showed that treatment of Mycobacterium tuberculosis infected mice with 5-OP-RU, a major antigen for MAIT cells, expands MAIT cells and enhances bacterial control. Here we treated M. tuberculosis...

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Detalles Bibliográficos
Autores principales: Sakai, Shunsuke, Lora, Nickiana E., Kauffman, Keith D., Dorosky, Danielle E., Oh, Sangmi, Namasivayam, Sivaranjani, Gomez, Felipe, Fleegle, Joel D., Arlehamn, Cecilia S. Lindestam, Sette, Alessandro, Sher, Alan, Freeman, Gordon J., Via, Laura E., Barry III, Clifton E., Barber, Daniel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217205/
https://www.ncbi.nlm.nih.gov/pubmed/34158594
http://dx.doi.org/10.1038/s41385-021-00425-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217205/
https://www.ncbi.nlm.nih.gov/pubmed/34158594
http://dx.doi.org/10.1038/s41385-021-00425-3

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