Cargando…

Phylogenomic analysis reveals persistence of gonococcal strains with reduced-susceptibility to extended-spectrum cephalosporins and mosaic penA-34

The recent emergence of strains of Neisseria gonorrhoeae associated with treatment failures to ceftriaxone, the foundation of current treatment options, has raised concerns over a future of untreatable gonorrhea. Current global data on gonococcal strains suggest that several lineages, predominately...

Descripción completa

Detalles Bibliográficos
Autores principales:	Thomas, Jesse C., Joseph, Sandeep J., Cartee, John C., Pham, Cau D., Schmerer, Matthew W., Schlanger, Karen, St. Cyr, Sancta B., Kersh, Ellen N., Raphael, Brian H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217231/ https://www.ncbi.nlm.nih.gov/pubmed/34155204 http://dx.doi.org/10.1038/s41467-021-24072-1

Ejemplares similares

Update to CDC's Treatment Guidelines for Gonococcal Infection, 2020
por: St. Cyr, Sancta, et al.
Publicado: (2020)

434. Concurrent Gonococcal Infections with Differing Susceptibility Results from the Enhanced Gonococcal Isolate Surveillance Project (eGISP)
por: St. Cyr, Sancta, et al.
Publicado: (2019)

Notes from the Field: First Case in the United States of Neisseria gonorrhoeae Harboring Emerging Mosaic penA60 Allele, Conferring Reduced Susceptibility to Cefixime and Ceftriaxone
por: Picker, Michael A., et al.
Publicado: (2020)

Neisseria gonorrhoeae and extended-spectrum cephalosporins in California: surveillance and molecular detection of mosaic penA
por: Gose, Severin, et al.
Publicado: (2013)

1167. Trends in Multi-Drug-Resistant Gonorrhea, Gonococcal Isolate Surveillance Project, United States, 1987–2016
por: St. Cyr, Sancta, et al.
Publicado: (2018)

Genomic analysis of 1710 surveillance-based Neisseria gonorrhoeae isolates from the USA in 2019 identifies predominant strain types and chromosomal antimicrobial-resistance determinants
por: Reimche, Jennifer L., et al.
Publicado: (2023)

Emergence and Spread of Cephalosporin-Resistant Neisseria gonorrhoeae with Mosaic penA Alleles, South Korea, 2012–2017
por: Lee, Hyukmin, et al.
Publicado: (2019)

Real-Time PCR Targeting Mosaic penA XXXIV for Prediction of Extended-Spectrum Cephalosporins Susceptibility in Clinical Neisseria Gonorrheae Isolates
por: Hemarajata, Peera, et al.
Publicado: (2017)

Impact of the gonococcal FC428 penA allele 60.001 on ceftriaxone resistance and biological fitness
por: Zhou, Ke, et al.
Publicado: (2020)

Mechanistic Basis for Decreased Antimicrobial Susceptibility in a Clinical Isolate of Neisseria gonorrhoeae Possessing a Mosaic-Like mtr Efflux Pump Locus
por: Rouquette-Loughlin, Corinne E., et al.
Publicado: (2018)

Evaluating spatially adaptive guidelines for the treatment of gonorrhea to reduce the incidence of gonococcal infection and increase the effective lifespan of antibiotics
por: Yaesoubi, Reza, et al.
Publicado: (2022)

In Vivo-Selected Compensatory Mutations Restore the Fitness Cost of Mosaic penA Alleles That Confer Ceftriaxone Resistance in Neisseria gonorrhoeae
por: Vincent, Leah R., et al.
Publicado: (2018)

A Culture Collection of 50 Neisseria gonorrhoeae Isolates
por: Liu, H., et al.
Publicado: (2020)

Ceftriaxone-resistant, multidrug-resistant Neisseria gonorrhoeae with a novel mosaic penA-237.001 gene, France, June 2022
por: Berçot, Béatrice, et al.
Publicado: (2022)

Sequence heterogeneity of the PenA carbapenemase in clinical isolates of Burkholderia multivorans
por: Becka, Scott A., et al.
Publicado: (2018)

2687. Tetracycline Resistance in Neisseria gonorrhoeae Isolates Among Transgender Women and Men Who Have Sex with Men — eGISP and SURRG, 2018–2021
por: Wondmeneh, Sarah, et al.
Publicado: (2023)

Dissemination and genome analysis of high-level ceftriaxone-resistant penA 60.001 Neisseria gonorrhoeae strains from the Guangdong Gonococcal antibiotics susceptibility Programme (GD-GASP), 2016–2019
por: Lin, Xiaomian, et al.
Publicado: (2022)

Molecular Investigations of PenA-mediated β-lactam Resistance in Burkholderia pseudomallei
por: Rholl, Drew A., et al.
Publicado: (2011)

Characterization of a Neisseria gonorrhoeae Ciprofloxacin panel for an antimicrobial resistant Isolate Bank
por: Liu, Hsi, et al.
Publicado: (2022)

Identification of ceftriaxone-resistant Neisseria gonorrhoeae FC428 clone and isolates harboring a novel mosaic penA gene in Chengdu in 2019–2020
por: Wang, Di, et al.
Publicado: (2023)

Gonococcal Clinical Strains Bearing a Common gdhR Single Nucleotide Polymorphism That Results in Enhanced Expression of the Virulence Gene lctP Frequently Possess a mtrR Promoter Mutation That Decreases Antibiotic Susceptibility
por: Ayala, Julio C., et al.
Publicado: (2022)

Increase in Multidrug Resistant Neisseria gonorrhoeae FC428-Like Isolates Harboring the Mosaic penA 60.001 Gene, in Nanjing, China (2017-2020)
por: Zhao, Yuanyuan, et al.
Publicado: (2023)

PenA, a penicillin-binding protein-type thioesterase specialized for small peptide cyclization
por: Matsuda, Kenichi, et al.
Publicado: (2021)

Genomic Epidemiology of Gonococcal Resistance to Extended-Spectrum Cephalosporins, Macrolides, and Fluoroquinolones in the United States, 2000–2013
por: Grad, Yonatan H., et al.
Publicado: (2016)

Genetic Similarity of Gonococcal Homologs to Meningococcal Outer Membrane Proteins of Serogroup B Vaccine
por: Marjuki, Henju, et al.
Publicado: (2019)

Transcriptional and post-transcriptional regulation of PenA β-lactamase in acquired Burkholderia pseudomallei β-lactam resistance
por: Chirakul, Sunisa, et al.
Publicado: (2018)

Direct Detection of penA Gene Associated with Ceftriaxone-Resistant Neisseria gonorrhoeae FC428 Strain by Using PCR
por: Whiley, David M., et al.
Publicado: (2018)

Gonococcal conjunctivitis after incomplete treatment of gonococcal urethritis
por: Wang, Mei-Fang, et al.
Publicado: (2019)

Penas alternativas a la pena de prisión
por: Abad Sánchez, Teresa Margarita
Publicado: (2013)

Loop-Mediated Isothermal Amplification Assay for Identifying Neisseria gonorrhoeae Nonmosaic penA-Targeting Strains Potentially Eradicable by Cefixime
por: Shimuta, Ken, et al.
Publicado: (2022)

Multidrug-resistant Neisseria gonorrhoeae isolate SE690: mosaic penA-60.001 gene causing ceftriaxone resistance internationally has spread to the more antimicrobial-susceptible genomic lineage, Sweden, September 2022
por: Golparian, Daniel, et al.
Publicado: (2023)

Gonococcal Arthritis
por: Malhotra, S. L.
Publicado: (1950)

Peñas arriba /
por: Pereda, José María de, 1833-1906
Publicado: (1984)

Peñas arriba
por: Pereda, José María de, 1833-1906
Publicado: (1939)

Peñas arriba /
por: Pereda, José María de, 1833-1906
Publicado: (1988)

La pena
por: Hentig, Hans von, 1887-1974
Publicado: (1967)

Peñas arriba
por: Pereda, José María de 1833-1906
Publicado: (1973)

Peñas arriba
por: Pereda, José María de, 1833-1906
Publicado: (1976)

Penas precoces
por: Kiš, Danilo, 1935-1989

Peñas arriba ; Sotileza
por: Pereda, José María de, 1833-1906
Publicado: (1966)

Cannot write session to /tmp/vufind_sessions/sess_qsb4g6imguhln45jei4d9etpmv