Cargando…
Drugs in COVID‐19 Clinical Trials: Predicting Transporter‐Mediated Drug‐Drug Interactions Using In Vitro Assays and Real‐World Data
Numerous drugs are currently under accelerated clinical investigation for the treatment of coronavirus disease 2019 (COVID‐19); however, well‐established safety and efficacy data for these drugs are limited. The goal of this study was to predict the potential of 25 small molecule drugs in clinical t...
Autores principales: | Yee, Sook Wah, Vora, Bianca, Oskotsky, Tomiko, Zou, Ling, Jakobsen, Sebastian, Enogieru, Osatohanmwen J., Koleske, Megan L., Kosti, Idit, Rödin, Mattias, Sirota, Marina, Giacomini, Kathleen M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217266/ https://www.ncbi.nlm.nih.gov/pubmed/33759449 http://dx.doi.org/10.1002/cpt.2236 |
Ejemplares similares
-
The Effects of Genetic Mutations and Drugs on the Activity of the Thiamine Transporter, SLC19A2
por: Enogieru, Osatohanmwen J., et al.
Publicado: (2021) -
Drug–nutrient interactions: discovering prescription drug inhibitors of the thiamine transporter ThTR-2 (SLC19A3)
por: Vora, Bianca, et al.
Publicado: (2020) -
Decreased Mortality Rate Among COVID-19 Patients Prescribed Statins: Data From Electronic Health Records in the US
por: Marić, Ivana, et al.
Publicado: (2021) -
Transcriptomics-based drug repositioning pipeline identifies therapeutic candidates for COVID-19
por: Le, Brian L., et al.
Publicado: (2021) -
Transcriptomics-based drug repositioning pipeline identifies therapeutic candidates for COVID-19
por: Le, Brian L., et al.
Publicado: (2021)