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Fascin1 empowers YAP mechanotransduction and promotes cholangiocarcinoma development
Mechanical forces control cell behavior, including cancer progression. Cells sense forces through actomyosin to activate YAP. However, the regulators of F-actin dynamics playing relevant roles during mechanostransduction in vitro and in vivo remain poorly characterized. Here we identify the Fascin1...
Autores principales: | Pocaterra, Arianna, Scattolin, Gloria, Romani, Patrizia, Ament, Cindy, Ribback, Silvia, Chen, Xin, Evert, Matthias, Calvisi, Diego F., Dupont, Sirio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217270/ https://www.ncbi.nlm.nih.gov/pubmed/34155338 http://dx.doi.org/10.1038/s42003-021-02286-9 |
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