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An affinity-matured human monoclonal antibody targeting fusion loop epitope of dengue virus with in vivo therapeutic potency

Dengue virus (DENV), from the genus flavivirus of the family flaviviridae, causes serious health problems globally. Human monoclonal antibodies (HuMAb) can be used to elucidate the mechanisms of neutralization and antibody-dependent enhancement (ADE) of DENV infections, leading to the development of...

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Detalles Bibliográficos
Autores principales:	Kotaki, Tomohiro, Kurosu, Takeshi, Grinyo-Escuer, Ariadna, Davidson, Edgar, Churrotin, Siti, Okabayashi, Tamaki, Puiprom, Orapim, Mulyatno, Kris Cahyo, Sucipto, Teguh Hari, Doranz, Benjamin J., Ono, Ken-ichiro, Soegijanto, Soegeng, Kameoka, Masanori
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217507/ https://www.ncbi.nlm.nih.gov/pubmed/34155267 http://dx.doi.org/10.1038/s41598-021-92403-9

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