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Intracellular localisation of Mycobacterium tuberculosis affects efficacy of the antibiotic pyrazinamide

To be effective, chemotherapy against tuberculosis (TB) must kill the intracellular population of the pathogen, Mycobacterium tuberculosis. However, how host cell microenvironments affect antibiotic accumulation and efficacy remains unclear. Here, we use correlative light, electron, and ion microsco...

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Detalles Bibliográficos
Autores principales:	Santucci, Pierre, Greenwood, Daniel J., Fearns, Antony, Chen, Kai, Jiang, Haibo, Gutierrez, Maximiliano G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217510/ https://www.ncbi.nlm.nih.gov/pubmed/34155215 http://dx.doi.org/10.1038/s41467-021-24127-3

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