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Fight against COVID-19 with mRNA vaccines and interaction with Dermal fillers
The current coronavirus disease 2019 (COVID-19) outbreak has created a huge demand for rapid and high-volume vaccine manufacturing. Several new platform technologies and traditional manufacturing approaches are being used to meet this demand. Among them, the mRNA vaccine platform technology holds gr...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Vaccine Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217583/ https://www.ncbi.nlm.nih.gov/pubmed/34222128 http://dx.doi.org/10.7774/cevr.2021.10.2.151 |
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author | Ghasemi, Shohreh Dashti, Mahmood |
author_facet | Ghasemi, Shohreh Dashti, Mahmood |
author_sort | Ghasemi, Shohreh |
collection | PubMed |
description | The current coronavirus disease 2019 (COVID-19) outbreak has created a huge demand for rapid and high-volume vaccine manufacturing. Several new platform technologies and traditional manufacturing approaches are being used to meet this demand. Among them, the mRNA vaccine platform technology holds great promise for obtaining an emergency use authorization to facilitate immunization against SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), which causes the respiratory illness COVID-19. However, this is a new technology, which means that there is significant uncertainty about possible production at a large scale and speed. Vaccines of mRNA work by providing our cells with the genetic code to make viral proteins. Once proteins that do not cause any disease are produced, the body triggers an immune response against the virus, allowing them to develop immunity. mRNA can be used to make any protein theoretically. Still, it is much easier to produce than the proteins themselves or the inactivated and attenuated versions of viruses commonly used in vaccines, which makes this technique attractive, says mRNA specialist Norbert Pardi, at the University of Pennsylvania. |
format | Online Article Text |
id | pubmed-8217583 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The Korean Vaccine Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-82175832021-07-01 Fight against COVID-19 with mRNA vaccines and interaction with Dermal fillers Ghasemi, Shohreh Dashti, Mahmood Clin Exp Vaccine Res Brief Communication The current coronavirus disease 2019 (COVID-19) outbreak has created a huge demand for rapid and high-volume vaccine manufacturing. Several new platform technologies and traditional manufacturing approaches are being used to meet this demand. Among them, the mRNA vaccine platform technology holds great promise for obtaining an emergency use authorization to facilitate immunization against SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), which causes the respiratory illness COVID-19. However, this is a new technology, which means that there is significant uncertainty about possible production at a large scale and speed. Vaccines of mRNA work by providing our cells with the genetic code to make viral proteins. Once proteins that do not cause any disease are produced, the body triggers an immune response against the virus, allowing them to develop immunity. mRNA can be used to make any protein theoretically. Still, it is much easier to produce than the proteins themselves or the inactivated and attenuated versions of viruses commonly used in vaccines, which makes this technique attractive, says mRNA specialist Norbert Pardi, at the University of Pennsylvania. The Korean Vaccine Society 2021-05 2021-05-31 /pmc/articles/PMC8217583/ /pubmed/34222128 http://dx.doi.org/10.7774/cevr.2021.10.2.151 Text en © Korean Vaccine Society. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Brief Communication Ghasemi, Shohreh Dashti, Mahmood Fight against COVID-19 with mRNA vaccines and interaction with Dermal fillers |
title | Fight against COVID-19 with mRNA vaccines and interaction with Dermal fillers |
title_full | Fight against COVID-19 with mRNA vaccines and interaction with Dermal fillers |
title_fullStr | Fight against COVID-19 with mRNA vaccines and interaction with Dermal fillers |
title_full_unstemmed | Fight against COVID-19 with mRNA vaccines and interaction with Dermal fillers |
title_short | Fight against COVID-19 with mRNA vaccines and interaction with Dermal fillers |
title_sort | fight against covid-19 with mrna vaccines and interaction with dermal fillers |
topic | Brief Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217583/ https://www.ncbi.nlm.nih.gov/pubmed/34222128 http://dx.doi.org/10.7774/cevr.2021.10.2.151 |
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