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Fight against COVID-19 with mRNA vaccines and interaction with Dermal fillers

The current coronavirus disease 2019 (COVID-19) outbreak has created a huge demand for rapid and high-volume vaccine manufacturing. Several new platform technologies and traditional manufacturing approaches are being used to meet this demand. Among them, the mRNA vaccine platform technology holds gr...

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Detalles Bibliográficos
Autores principales: Ghasemi, Shohreh, Dashti, Mahmood
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Vaccine Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217583/
https://www.ncbi.nlm.nih.gov/pubmed/34222128
http://dx.doi.org/10.7774/cevr.2021.10.2.151
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author Ghasemi, Shohreh
Dashti, Mahmood
author_facet Ghasemi, Shohreh
Dashti, Mahmood
author_sort Ghasemi, Shohreh
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description The current coronavirus disease 2019 (COVID-19) outbreak has created a huge demand for rapid and high-volume vaccine manufacturing. Several new platform technologies and traditional manufacturing approaches are being used to meet this demand. Among them, the mRNA vaccine platform technology holds great promise for obtaining an emergency use authorization to facilitate immunization against SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), which causes the respiratory illness COVID-19. However, this is a new technology, which means that there is significant uncertainty about possible production at a large scale and speed. Vaccines of mRNA work by providing our cells with the genetic code to make viral proteins. Once proteins that do not cause any disease are produced, the body triggers an immune response against the virus, allowing them to develop immunity. mRNA can be used to make any protein theoretically. Still, it is much easier to produce than the proteins themselves or the inactivated and attenuated versions of viruses commonly used in vaccines, which makes this technique attractive, says mRNA specialist Norbert Pardi, at the University of Pennsylvania.
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spelling pubmed-82175832021-07-01 Fight against COVID-19 with mRNA vaccines and interaction with Dermal fillers Ghasemi, Shohreh Dashti, Mahmood Clin Exp Vaccine Res Brief Communication The current coronavirus disease 2019 (COVID-19) outbreak has created a huge demand for rapid and high-volume vaccine manufacturing. Several new platform technologies and traditional manufacturing approaches are being used to meet this demand. Among them, the mRNA vaccine platform technology holds great promise for obtaining an emergency use authorization to facilitate immunization against SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), which causes the respiratory illness COVID-19. However, this is a new technology, which means that there is significant uncertainty about possible production at a large scale and speed. Vaccines of mRNA work by providing our cells with the genetic code to make viral proteins. Once proteins that do not cause any disease are produced, the body triggers an immune response against the virus, allowing them to develop immunity. mRNA can be used to make any protein theoretically. Still, it is much easier to produce than the proteins themselves or the inactivated and attenuated versions of viruses commonly used in vaccines, which makes this technique attractive, says mRNA specialist Norbert Pardi, at the University of Pennsylvania. The Korean Vaccine Society 2021-05 2021-05-31 /pmc/articles/PMC8217583/ /pubmed/34222128 http://dx.doi.org/10.7774/cevr.2021.10.2.151 Text en © Korean Vaccine Society. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Communication
Ghasemi, Shohreh
Dashti, Mahmood
Fight against COVID-19 with mRNA vaccines and interaction with Dermal fillers
title Fight against COVID-19 with mRNA vaccines and interaction with Dermal fillers
title_full Fight against COVID-19 with mRNA vaccines and interaction with Dermal fillers
title_fullStr Fight against COVID-19 with mRNA vaccines and interaction with Dermal fillers
title_full_unstemmed Fight against COVID-19 with mRNA vaccines and interaction with Dermal fillers
title_short Fight against COVID-19 with mRNA vaccines and interaction with Dermal fillers
title_sort fight against covid-19 with mrna vaccines and interaction with dermal fillers
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217583/
https://www.ncbi.nlm.nih.gov/pubmed/34222128
http://dx.doi.org/10.7774/cevr.2021.10.2.151
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