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Noninvasive prediction of carotid artery atherosclerosis by multiple abdominal fat indices measured via ultrasonography

PURPOSE: The purpose of this study was to evaluate the efficiency of multiple abdominal fat indices as measured via ultrasonography for predicting the presence and severity of carotid artery atherosclerosis and to compare the predictive capacity of ultrasonographic measurements to that of anthropome...

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Autores principales: Hazem, Mohammed, Elsamman, Mahmoud, Bazeed, Shamardan, Zaki, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Ultrasound in Medicine 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217801/
https://www.ncbi.nlm.nih.gov/pubmed/33525857
http://dx.doi.org/10.14366/usg.20109
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author Hazem, Mohammed
Elsamman, Mahmoud
Bazeed, Shamardan
Zaki, Mohammed
author_facet Hazem, Mohammed
Elsamman, Mahmoud
Bazeed, Shamardan
Zaki, Mohammed
author_sort Hazem, Mohammed
collection PubMed
description PURPOSE: The purpose of this study was to evaluate the efficiency of multiple abdominal fat indices as measured via ultrasonography for predicting the presence and severity of carotid artery atherosclerosis and to compare the predictive capacity of ultrasonographic measurements to that of anthropometric measurements. METHODS: A total of 92 patients were included in this study. All participants underwent clinical and laboratory assessments, and anthropometric measurements were obtained. Ultrasound examinations were performed to measure the values of all abdominal fat indices and the intima-media thickness, as well as to detect the presence of atherosclerotic plaques. Univariate and multivariate logistic regression analyses were performed. RESULTS: In the multivariate analysis, significant associations were detected between carotid artery atherosclerosis and posterior right perinephric fat thickness (PRPFT) (hazard ratio [HR], 15.23; P<0.001), preperitoneal fat thickness (PPFT) (HR, 4.31; P=0.003), visceral adipose tissue volume (VAT) (HR, 7.61; P<0.001), visceral fat thickness (VFT) (HR, 8.84; P<0.001), the ratio of VFT to subcutaneous fat thickness (VFT/SCFT) (HR, 9.39; P<0.001), and waist-to-height ratio (WHtR) (HR, 2.65; P=0.046). In the multivariate analysis, significant associations were also detected between carotid artery plaque and PRPFT (HR, 7.09; P<0.001), the abdominal wall fat index (AFI) (HR, 3.58; P=0.010), and VFT/SCFT (HR, 4.17; P=0.006). CONCLUSION: Many abdominal fat indices as measured by ultrasound were found to be strong predictors of carotid artery atherosclerosis, including PRPFT, VFT/SCFT, VFT, VAT, PPFT, and WHtR. Moreover, PRPFT, VFT/SCFT, and AFI were identified as strong predictors of the presence of carotid artery plaque.
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spelling pubmed-82178012021-07-03 Noninvasive prediction of carotid artery atherosclerosis by multiple abdominal fat indices measured via ultrasonography Hazem, Mohammed Elsamman, Mahmoud Bazeed, Shamardan Zaki, Mohammed Ultrasonography Original Article PURPOSE: The purpose of this study was to evaluate the efficiency of multiple abdominal fat indices as measured via ultrasonography for predicting the presence and severity of carotid artery atherosclerosis and to compare the predictive capacity of ultrasonographic measurements to that of anthropometric measurements. METHODS: A total of 92 patients were included in this study. All participants underwent clinical and laboratory assessments, and anthropometric measurements were obtained. Ultrasound examinations were performed to measure the values of all abdominal fat indices and the intima-media thickness, as well as to detect the presence of atherosclerotic plaques. Univariate and multivariate logistic regression analyses were performed. RESULTS: In the multivariate analysis, significant associations were detected between carotid artery atherosclerosis and posterior right perinephric fat thickness (PRPFT) (hazard ratio [HR], 15.23; P<0.001), preperitoneal fat thickness (PPFT) (HR, 4.31; P=0.003), visceral adipose tissue volume (VAT) (HR, 7.61; P<0.001), visceral fat thickness (VFT) (HR, 8.84; P<0.001), the ratio of VFT to subcutaneous fat thickness (VFT/SCFT) (HR, 9.39; P<0.001), and waist-to-height ratio (WHtR) (HR, 2.65; P=0.046). In the multivariate analysis, significant associations were also detected between carotid artery plaque and PRPFT (HR, 7.09; P<0.001), the abdominal wall fat index (AFI) (HR, 3.58; P=0.010), and VFT/SCFT (HR, 4.17; P=0.006). CONCLUSION: Many abdominal fat indices as measured by ultrasound were found to be strong predictors of carotid artery atherosclerosis, including PRPFT, VFT/SCFT, VFT, VAT, PPFT, and WHtR. Moreover, PRPFT, VFT/SCFT, and AFI were identified as strong predictors of the presence of carotid artery plaque. Korean Society of Ultrasound in Medicine 2021-07 2020-10-24 /pmc/articles/PMC8217801/ /pubmed/33525857 http://dx.doi.org/10.14366/usg.20109 Text en Copyright © 2021 Korean Society of Ultrasound in Medicine (KSUM) https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Hazem, Mohammed
Elsamman, Mahmoud
Bazeed, Shamardan
Zaki, Mohammed
Noninvasive prediction of carotid artery atherosclerosis by multiple abdominal fat indices measured via ultrasonography
title Noninvasive prediction of carotid artery atherosclerosis by multiple abdominal fat indices measured via ultrasonography
title_full Noninvasive prediction of carotid artery atherosclerosis by multiple abdominal fat indices measured via ultrasonography
title_fullStr Noninvasive prediction of carotid artery atherosclerosis by multiple abdominal fat indices measured via ultrasonography
title_full_unstemmed Noninvasive prediction of carotid artery atherosclerosis by multiple abdominal fat indices measured via ultrasonography
title_short Noninvasive prediction of carotid artery atherosclerosis by multiple abdominal fat indices measured via ultrasonography
title_sort noninvasive prediction of carotid artery atherosclerosis by multiple abdominal fat indices measured via ultrasonography
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217801/
https://www.ncbi.nlm.nih.gov/pubmed/33525857
http://dx.doi.org/10.14366/usg.20109
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