Cargando…

Profiling of 520 Candidate Genes in 50 Surgically Treated Chinese Small Cell Lung Cancer Patients

Small cell lung cancer (SCLC) is one of the severe malignancies with high mortality. Surgically resected tumor tissues from 50 Chinese SCLC patients were collected for next-generation sequencing to detect 520 cancer‐related genes. The most frequently altered genes were TP53 (94.0%), RB1 (86.0%), LRP...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yuan, Ting, Wang, Xin, Sun, Sijin, Cao, Zheng, Feng, Xiaoli, Gao, Yibo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217828/ https://www.ncbi.nlm.nih.gov/pubmed/34168983 http://dx.doi.org/10.3389/fonc.2021.644434

Ejemplares similares

The Deubiquitinase USP13 Maintains Cancer Cell Stemness by Promoting FASN Stability in Small Cell Lung Cancer
por: Wang, Juhong, et al.
Publicado: (2022)

Enhanced Cytotoxic Activity of Mitochondrial Mechanical Effectors in Human Lung Carcinoma H520 Cells: Pharmaceutical Implications for Cancer Therapy
por: González Rubio, Sergio, et al.
Publicado: (2018)

Role of miR-520b in non-small cell lung cancer
por: Zhang, Linlin, et al.
Publicado: (2018)

Clinical characteristics and gene mutation profiles of chronic obstructive pulmonary disease in non-small cell lung cancer
por: Yuan, Lin, et al.
Publicado: (2022)

mRNA and microRNA expression profiles of radioresistant NCI-H520 non-small cell lung cancer cells
por: GUO, WEI, et al.
Publicado: (2015)

MiR-520a-5p/PPP5C regulation pattern is identified as the key to gemcitabine resistance in pancreatic cancer
por: Fu, Ruibiao, et al.
Publicado: (2022)

Resistance Profile of Osimertinib in Pre-treated Patients With EGFR T790M-Mutated Non-small Cell Lung Cancer
por: Fernandes, Maria Gabriela O., et al.
Publicado: (2021)

Genomic profiles of renal cell carcinoma in a small Chinese cohort
por: Tai, Sheng, et al.
Publicado: (2023)

MiR‐520b promotes the progression of non‐small cell lung cancer through activating Hedgehog pathway
por: Liu, Xiaoming, et al.
Publicado: (2018)

Surgical Management of Stage IIIA Non-Small Cell Lung Cancer
por: Van Schil, Paul E., et al.
Publicado: (2017)

Association Between Triglyceride Glucose Index and Non-Small Cell Lung Cancer Risk in Chinese Population
por: Yan, Xin, et al.
Publicado: (2021)

Profiling Oncogenic Germline Mutations in Unselected Chinese Lung Cancer Patients
por: Yang, Jie, et al.
Publicado: (2021)

Prognostic Impact of Metabolism Reprogramming Markers Acetyl-CoA Synthetase 2 Phosphorylation and Ketohexokinase-A Expression in Non-Small-Cell Lung Carcinoma
por: Yang, Xueying, et al.
Publicado: (2019)

520 CTSA Search Solutions
por: Tafuto, Barbara, et al.
Publicado: (2022)

Prognostic significance of eighth edition TNM stage criteria in combined small-cell lung cancer
por: Zhao, Ziran, et al.
Publicado: (2023)

Practice Patterns of Treatment Strategy of Limited-Stage Small-Cell Lung Cancer: Survey of Chinese Oncologists
por: Xu, Chang, et al.
Publicado: (2022)

Risk of adenoma recurrence after polypectomy in patients younger than 50 years vs. 50 years old and over with diminutive or small adenomas
por: Cai, Sicheng, et al.
Publicado: (2022)

Use of the prognostic nutrition index as a predictive biomarker in small-cell lung cancer patients undergoing immune checkpoint inhibitor treatment in the Chinese alpine region
por: Wu, Yunjiao, et al.
Publicado: (2023)

Circular RNA FNDC3B Protects Oral Squamous Cell Carcinoma Cells From Ferroptosis and Contributes to the Malignant Progression by Regulating miR-520d-5p/SLC7A11 Axis
por: Yang, Jie, et al.
Publicado: (2021)

Profiling Receptor Tyrosine Kinase Fusions in Chinese Breast Cancers
por: Tao, Zhonghua, et al.
Publicado: (2021)

Characterizing microbiota and metabolomics analysis to identify candidate biomarkers in lung cancer
por: Liu, Bo, et al.
Publicado: (2022)

Genomic profiling and sites of metastasis in non-small cell lung cancer
por: Chan, Kok Hoe, et al.
Publicado: (2023)

Choline Kinase Alpha2 Promotes Lipid Droplet Lipolysis in Non-Small-Cell Lung Carcinoma
por: Zhu, Rongxuan, et al.
Publicado: (2022)

Surgical Outcomes After Neoadjuvant Chemoimmunotherapy for Resectable Non-Small Cell Lung Cancer
por: Hu, Yan, et al.
Publicado: (2021)

Prediction of Clinical Outcome in Locally Advanced Non-Small Cell Lung Cancer Patients Treated With Chemoradiotherapy by Plasma Markers
por: Sui, Xin, et al.
Publicado: (2021)

Combining stereotactic body radiotherapy with immunotherapy in stage IV non-small cell lung cancer
por: Liu, Xiaoli, et al.
Publicado: (2023)

Genetic Alteration Profiling of Chinese Lung Adenocarcinoma and Its Effect on Targeted Therapy Efficacy
por: Liu, Jie, et al.
Publicado: (2021)

Identification of IRAK1BP1 as a candidate prognostic factor in lung adenocarcinoma
por: Guo, Lei, et al.
Publicado: (2023)

Prognostic Value of Inflammatory Biomarkers in Patients With Stage I Lung Adenocarcinoma Treated With Surgical Dissection
por: Shen, Yu-Jia, et al.
Publicado: (2021)

Impact of Adjuvant Therapy on Survival in Surgically Resected Limited-Stage Small Cell Lung Cancer
por: Li, Di, et al.
Publicado: (2021)

Tumor grade-associated genomic mutations in Chinese patients with non-small cell lung cancer
por: Wang, Yang, et al.
Publicado: (2023)

The Application of Combined Immune Checkpoint Inhibitor Modalities in Previously Treated Non-Small Cell Lung Cancer Patients and the Associations Thereof With the Lung Immune Prognostic Index
por: Zhang, Ting, et al.
Publicado: (2021)

Genomic Profiling Reveals Novel Predictive Biomarkers for Chemo-Radiotherapy Efficacy and Thoracic Toxicity in Non-Small-Cell Lung Cancer
por: He, Kewen, et al.
Publicado: (2022)

Peripheral Blood Biomarkers Associated With Outcome in Non-small Cell Lung Cancer Patients Treated With Nivolumab and Durvalumab Monotherapy
por: Jiang, Meilin, et al.
Publicado: (2020)

Identification of Immune Subtypes and Candidate mRNA Vaccine Antigens in Small Cell Lung Cancer
por: Wei, Yuanfeng, et al.
Publicado: (2023)

Survival Benefit and Genetic Profile of Pemetrexed as Initial Chemotherapy in Selected Chinese Patients With Advanced Lung Adenocarcinoma
por: Guo, Long-Hua, et al.
Publicado: (2020)

Identification of Prognostic Signature and Gliclazide as Candidate Drugs in Lung Adenocarcinoma
por: Cheng, Yang, et al.
Publicado: (2021)

Multi-Omics Integration-Based Prioritisation of Competing Endogenous RNA Regulation Networks in Small Cell Lung Cancer: Molecular Characteristics and Drug Candidates
por: Wang, Xiao-Jun, et al.
Publicado: (2022)

The radiosensitization effects of Endostar on human lung squamous cancer cells H-520
por: You, Zhen Y, et al.
Publicado: (2010)

MiR-520f acts as a biomarker for the diagnosis of lung cancer
por: Zhou, Yingyan, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_j1p0mob071r1m3koa4al22sa4u