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Intravenously delivered multilineage-differentiating stress enduring cells dampen excessive glutamate metabolism and microglial activation in experimental perinatal hypoxic ischemic encephalopathy

Perinatal hypoxic ischemic encephalopathy (HIE) results in serious neurological dysfunction and mortality. Clinical trials of multilineage-differentiating stress enduring cells (Muse cells) have commenced in stroke using intravenous delivery of donor-derived Muse cells. Here, we investigated the the...

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Detalles Bibliográficos
Autores principales: Suzuki, Toshihiko, Sato, Yoshiaki, Kushida, Yoshihiro, Tsuji, Masahiro, Wakao, Shohei, Ueda, Kazuto, Imai, Kenji, Iitani, Yukako, Shimizu, Shinobu, Hida, Hideki, Temma, Takashi, Saito, Shigeyoshi, Iida, Hidehiro, Mizuno, Masaaki, Takahashi, Yoshiyuki, Dezawa, Mari, Borlongan, Cesar V, Hayakawa, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217885/
https://www.ncbi.nlm.nih.gov/pubmed/33222596
http://dx.doi.org/10.1177/0271678X20972656