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Alprostadil associated with low molecular weight heparin to treat limb ischemia caused by SARS-CoV2

The current coronavirus pandemic has already taken a great toll globally, causing massive morbidity and mortality. One of its severe forms is a thrombophilic state that can damage several systems. This article reports the case of 60-year-old female patient who presented with mild flu symptoms, which...

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Detalles Bibliográficos
Autores principales: Manhanelli, Marcos Antonio Bonacorso, Duarte, Eliud Garcia, Mariuba, Jamil Victor de Oliveira, Linardi, Fábio, Costa, José Augusto, Gali, Julio Cesar, Yoshida, Winston Bonetti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV) 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8218011/
https://www.ncbi.nlm.nih.gov/pubmed/34211521
http://dx.doi.org/10.1590/1677-5449.200072
Descripción
Sumario:The current coronavirus pandemic has already taken a great toll globally, causing massive morbidity and mortality. One of its severe forms is a thrombophilic state that can damage several systems. This article reports the case of 60-year-old female patient who presented with mild flu symptoms, which turned out to be a SARS-CoV2 infection, and ended up developing arterial thrombosis with limb ischemia in a private care hospital in Sorocaba, São Paulo, Brazil. Considering this progression, we decided to intervene with low molecular weight heparin and Alprostadil, achieving a good clinical outcome. Our description aims to identify key points and clinical signs that offer evidence of the therapeutic window and a treatment option for coagulatory presentations of COVID-19.