Alprostadil associated with low molecular weight heparin to treat limb ischemia caused by SARS-CoV2

The current coronavirus pandemic has already taken a great toll globally, causing massive morbidity and mortality. One of its severe forms is a thrombophilic state that can damage several systems. This article reports the case of 60-year-old female patient who presented with mild flu symptoms, which...

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Autores principales: Manhanelli, Marcos Antonio Bonacorso, Duarte, Eliud Garcia, Mariuba, Jamil Victor de Oliveira, Linardi, Fábio, Costa, José Augusto, Gali, Julio Cesar, Yoshida, Winston Bonetti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV) 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8218011/
https://www.ncbi.nlm.nih.gov/pubmed/34211521
http://dx.doi.org/10.1590/1677-5449.200072
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author Manhanelli, Marcos Antonio Bonacorso
Duarte, Eliud Garcia
Mariuba, Jamil Victor de Oliveira
Linardi, Fábio
Costa, José Augusto
Gali, Julio Cesar
Yoshida, Winston Bonetti
Gali, Julio Cesar
author_facet Manhanelli, Marcos Antonio Bonacorso
Duarte, Eliud Garcia
Mariuba, Jamil Victor de Oliveira
Linardi, Fábio
Costa, José Augusto
Gali, Julio Cesar
Yoshida, Winston Bonetti
Gali, Julio Cesar
author_sort Manhanelli, Marcos Antonio Bonacorso
collection PubMed
description The current coronavirus pandemic has already taken a great toll globally, causing massive morbidity and mortality. One of its severe forms is a thrombophilic state that can damage several systems. This article reports the case of 60-year-old female patient who presented with mild flu symptoms, which turned out to be a SARS-CoV2 infection, and ended up developing arterial thrombosis with limb ischemia in a private care hospital in Sorocaba, São Paulo, Brazil. Considering this progression, we decided to intervene with low molecular weight heparin and Alprostadil, achieving a good clinical outcome. Our description aims to identify key points and clinical signs that offer evidence of the therapeutic window and a treatment option for coagulatory presentations of COVID-19.
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spelling pubmed-82180112021-06-30 Alprostadil associated with low molecular weight heparin to treat limb ischemia caused by SARS-CoV2 Manhanelli, Marcos Antonio Bonacorso Duarte, Eliud Garcia Mariuba, Jamil Victor de Oliveira Linardi, Fábio Costa, José Augusto Gali, Julio Cesar Yoshida, Winston Bonetti Gali, Julio Cesar J Vasc Bras Case Report The current coronavirus pandemic has already taken a great toll globally, causing massive morbidity and mortality. One of its severe forms is a thrombophilic state that can damage several systems. This article reports the case of 60-year-old female patient who presented with mild flu symptoms, which turned out to be a SARS-CoV2 infection, and ended up developing arterial thrombosis with limb ischemia in a private care hospital in Sorocaba, São Paulo, Brazil. Considering this progression, we decided to intervene with low molecular weight heparin and Alprostadil, achieving a good clinical outcome. Our description aims to identify key points and clinical signs that offer evidence of the therapeutic window and a treatment option for coagulatory presentations of COVID-19. Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV) 2020-11-30 /pmc/articles/PMC8218011/ /pubmed/34211521 http://dx.doi.org/10.1590/1677-5449.200072 Text en https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Manhanelli, Marcos Antonio Bonacorso
Duarte, Eliud Garcia
Mariuba, Jamil Victor de Oliveira
Linardi, Fábio
Costa, José Augusto
Gali, Julio Cesar
Yoshida, Winston Bonetti
Gali, Julio Cesar
Alprostadil associated with low molecular weight heparin to treat limb ischemia caused by SARS-CoV2
title Alprostadil associated with low molecular weight heparin to treat limb ischemia caused by SARS-CoV2
title_full Alprostadil associated with low molecular weight heparin to treat limb ischemia caused by SARS-CoV2
title_fullStr Alprostadil associated with low molecular weight heparin to treat limb ischemia caused by SARS-CoV2
title_full_unstemmed Alprostadil associated with low molecular weight heparin to treat limb ischemia caused by SARS-CoV2
title_short Alprostadil associated with low molecular weight heparin to treat limb ischemia caused by SARS-CoV2
title_sort alprostadil associated with low molecular weight heparin to treat limb ischemia caused by sars-cov2
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8218011/
https://www.ncbi.nlm.nih.gov/pubmed/34211521
http://dx.doi.org/10.1590/1677-5449.200072
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