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Diagnostic accuracy of SPECT/CT arthrography in patients with suspected aseptic joint prostheses loosening

PURPOSE: To evaluate the diagnostic accuracy of SPECT/CT arthrography in patients with suspected aseptic prosthesis loosening following hip and knee arthroplasty. METHODS: A retrospective review of 63 SPECT/CT arthrogram studies (36 knees and 27 hips) between February 1, 2013, and July 1, 2018, was...

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Autores principales: Bao, Bo, Liu, Crystal S., Masson, Edward C. O., Abele, Jonathan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8218161/
https://www.ncbi.nlm.nih.gov/pubmed/34181120
http://dx.doi.org/10.1186/s41824-021-00098-y
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author Bao, Bo
Liu, Crystal S.
Masson, Edward C. O.
Abele, Jonathan T.
author_facet Bao, Bo
Liu, Crystal S.
Masson, Edward C. O.
Abele, Jonathan T.
author_sort Bao, Bo
collection PubMed
description PURPOSE: To evaluate the diagnostic accuracy of SPECT/CT arthrography in patients with suspected aseptic prosthesis loosening following hip and knee arthroplasty. METHODS: A retrospective review of 63 SPECT/CT arthrogram studies (36 knees and 27 hips) between February 1, 2013, and July 1, 2018, was conducted. All patients underwent clinical and radiologic evaluation as part of their assessment for persistent pain following hip and knee arthroplasty. The detection of tracer activity along the bone-prosthetic interface on SPECT/CT suggests aseptic loosening. Operative assessment as well as clinical/radiologic follow-up at a minimum of 1 year was used as the reference standard. RESULTS: The sensitivity and specificity of SPECT/CT for detection of aseptic loosening was 6/7 (86%) and 55/56 (98%), respectively. This gives a positive predictive value (PPV) of 6/7 (86%), a negative predictive value (NPV) of 55/56 (98%), and a diagnostic accuracy of 61/63 (97%). CONCLUSION: SPECT/CT arthrography has a high diagnostic accuracy (97%) in the evaluation of loosening of both hip and knee arthroplasties in patients with persistent post-procedural pain.
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spelling pubmed-82181612021-06-24 Diagnostic accuracy of SPECT/CT arthrography in patients with suspected aseptic joint prostheses loosening Bao, Bo Liu, Crystal S. Masson, Edward C. O. Abele, Jonathan T. Eur J Hybrid Imaging Original Article PURPOSE: To evaluate the diagnostic accuracy of SPECT/CT arthrography in patients with suspected aseptic prosthesis loosening following hip and knee arthroplasty. METHODS: A retrospective review of 63 SPECT/CT arthrogram studies (36 knees and 27 hips) between February 1, 2013, and July 1, 2018, was conducted. All patients underwent clinical and radiologic evaluation as part of their assessment for persistent pain following hip and knee arthroplasty. The detection of tracer activity along the bone-prosthetic interface on SPECT/CT suggests aseptic loosening. Operative assessment as well as clinical/radiologic follow-up at a minimum of 1 year was used as the reference standard. RESULTS: The sensitivity and specificity of SPECT/CT for detection of aseptic loosening was 6/7 (86%) and 55/56 (98%), respectively. This gives a positive predictive value (PPV) of 6/7 (86%), a negative predictive value (NPV) of 55/56 (98%), and a diagnostic accuracy of 61/63 (97%). CONCLUSION: SPECT/CT arthrography has a high diagnostic accuracy (97%) in the evaluation of loosening of both hip and knee arthroplasties in patients with persistent post-procedural pain. Springer International Publishing 2021-02-28 /pmc/articles/PMC8218161/ /pubmed/34181120 http://dx.doi.org/10.1186/s41824-021-00098-y Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Bao, Bo
Liu, Crystal S.
Masson, Edward C. O.
Abele, Jonathan T.
Diagnostic accuracy of SPECT/CT arthrography in patients with suspected aseptic joint prostheses loosening
title Diagnostic accuracy of SPECT/CT arthrography in patients with suspected aseptic joint prostheses loosening
title_full Diagnostic accuracy of SPECT/CT arthrography in patients with suspected aseptic joint prostheses loosening
title_fullStr Diagnostic accuracy of SPECT/CT arthrography in patients with suspected aseptic joint prostheses loosening
title_full_unstemmed Diagnostic accuracy of SPECT/CT arthrography in patients with suspected aseptic joint prostheses loosening
title_short Diagnostic accuracy of SPECT/CT arthrography in patients with suspected aseptic joint prostheses loosening
title_sort diagnostic accuracy of spect/ct arthrography in patients with suspected aseptic joint prostheses loosening
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8218161/
https://www.ncbi.nlm.nih.gov/pubmed/34181120
http://dx.doi.org/10.1186/s41824-021-00098-y
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