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Unlocking Iminium Catalysis in Artificial Enzymes to Create a Friedel–Crafts Alkylase
[Image: see text] The construction and engineering of artificial enzymes consisting of abiological catalytic moieties incorporated into protein scaffolds is a promising strategy to realize non-natural mechanisms in biocatalysis. Here, we show that incorporation of the noncanonical amino acid para-am...
Autores principales: | Leveson-Gower, Reuben B., Zhou, Zhi, Drienovská, Ivana, Roelfes, Gerard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8218303/ https://www.ncbi.nlm.nih.gov/pubmed/34168902 http://dx.doi.org/10.1021/acscatal.1c00996 |
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