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Assessment of liver disease in patients with chronic hepatitis C and unhealthy alcohol use
Hepatitis C virus (HCV) infection and unhealthy alcohol use are major drivers of the burden of liver disease worldwide and commonly co-occur. Assessment of underlying liver damage is a cornerstone of the clinical care of patients with chronic HCV infection and/or unhealthy alcohol use because many o...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Baishideng Publishing Group Inc
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8218351/ https://www.ncbi.nlm.nih.gov/pubmed/34163107 http://dx.doi.org/10.3748/wjg.v27.i23.3223 |
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author | Fuster, Daniel García-Calvo, Xavier Zuluaga, Paola Bolao, Ferran Muga, Robert |
author_facet | Fuster, Daniel García-Calvo, Xavier Zuluaga, Paola Bolao, Ferran Muga, Robert |
author_sort | Fuster, Daniel |
collection | PubMed |
description | Hepatitis C virus (HCV) infection and unhealthy alcohol use are major drivers of the burden of liver disease worldwide and commonly co-occur. Assessment of underlying liver damage is a cornerstone of the clinical care of patients with chronic HCV infection and/or unhealthy alcohol use because many of them are diagnosed at advanced stages of disease. Early diagnosis of liver disease before decompensated liver cirrhosis becomes established is essential for treatment with direct acting antivirals and/or abstinence from alcohol consumption, which are the main therapeutic approaches for clinical management. In this review, we discuss current knowledge around the use of non-invasive methods to assess liver disease, such as abdominal ultrasound, controlled attenuation parameter, transient elastography, magnetic resonance imaging, and indices based on serum markers of liver injury. |
format | Online Article Text |
id | pubmed-8218351 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Baishideng Publishing Group Inc |
record_format | MEDLINE/PubMed |
spelling | pubmed-82183512021-06-22 Assessment of liver disease in patients with chronic hepatitis C and unhealthy alcohol use Fuster, Daniel García-Calvo, Xavier Zuluaga, Paola Bolao, Ferran Muga, Robert World J Gastroenterol Review Hepatitis C virus (HCV) infection and unhealthy alcohol use are major drivers of the burden of liver disease worldwide and commonly co-occur. Assessment of underlying liver damage is a cornerstone of the clinical care of patients with chronic HCV infection and/or unhealthy alcohol use because many of them are diagnosed at advanced stages of disease. Early diagnosis of liver disease before decompensated liver cirrhosis becomes established is essential for treatment with direct acting antivirals and/or abstinence from alcohol consumption, which are the main therapeutic approaches for clinical management. In this review, we discuss current knowledge around the use of non-invasive methods to assess liver disease, such as abdominal ultrasound, controlled attenuation parameter, transient elastography, magnetic resonance imaging, and indices based on serum markers of liver injury. Baishideng Publishing Group Inc 2021-06-21 2021-06-21 /pmc/articles/PMC8218351/ /pubmed/34163107 http://dx.doi.org/10.3748/wjg.v27.i23.3223 Text en ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
spellingShingle | Review Fuster, Daniel García-Calvo, Xavier Zuluaga, Paola Bolao, Ferran Muga, Robert Assessment of liver disease in patients with chronic hepatitis C and unhealthy alcohol use |
title | Assessment of liver disease in patients with chronic hepatitis C and unhealthy alcohol use |
title_full | Assessment of liver disease in patients with chronic hepatitis C and unhealthy alcohol use |
title_fullStr | Assessment of liver disease in patients with chronic hepatitis C and unhealthy alcohol use |
title_full_unstemmed | Assessment of liver disease in patients with chronic hepatitis C and unhealthy alcohol use |
title_short | Assessment of liver disease in patients with chronic hepatitis C and unhealthy alcohol use |
title_sort | assessment of liver disease in patients with chronic hepatitis c and unhealthy alcohol use |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8218351/ https://www.ncbi.nlm.nih.gov/pubmed/34163107 http://dx.doi.org/10.3748/wjg.v27.i23.3223 |
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