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Pharmacokinetics and tolerance of repeated oral administration of 5-fluorocytosine in healthy dogs

BACKGROUND: 5-fluorocytosine is a pyrimidine and a fluorinated cytosine analog mainly used as an antifungal agent. It is a precursor of 5-fluorouracil, which possesses anticancer properties. To reduce systemic toxicity of 5-fluorouracil during chemotherapy, 5- fluorocytosine can be used as a targete...

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Detalles Bibliográficos
Autores principales:	Béguin, Jérémy, Kohlhauer, Matthias, Laloy, Eve, Degorce, Frédérique, Moreau, Baptiste, Quéméneur, Éric, Erbs, Philippe, Klonjkowski, Bernard, Maurey, Christelle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8218522/ https://www.ncbi.nlm.nih.gov/pubmed/34154593 http://dx.doi.org/10.1186/s12917-021-02927-5

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