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Safety, Tolerability, and Pharmacokinetics of NTM-1632, a Novel Mixture of Three Monoclonal Antibodies against Botulinum Toxin B
Botulism is a rare, life-threatening paralytic disease caused by Clostridium botulinum neurotoxin (BoNT). Available treatments, including an equine antitoxin and human immune globulin, are given postexposure and challenging to produce and administer. NTM-1632 is an equimolar mixture of 3 human IgG m...
Autores principales: | Guptill, J. T., Raja, S. M., Juel, V. C., Walter, E. B., Cohen-Wolkowiez, M., Hill, H., Sendra, E., Hauser, B., Jackson, P., Swamy, G. K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8218613/ https://www.ncbi.nlm.nih.gov/pubmed/33875433 http://dx.doi.org/10.1128/AAC.02329-20 |
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