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Microevolution of Mycobacterium tuberculosis Subpopulations and Heteroresistance in a Patient Receiving 27 Years of Tuberculosis Treatment in Germany

Preexisting and newly emerging resistant pathogen subpopulations (heteroresistance) are potential risk factors for treatment failure of multi/extensively drug resistant (MDR/XDR) tuberculosis (TB). Intrapatient evolutionary dynamics of Mycobacterium tuberculosis complex (Mtbc) strains and their impl...

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Detalles Bibliográficos
Autores principales:	Sonnenkalb, Lindsay, Strohe, Gerald, Dreyer, Viola, Andres, Sönke, Hillemann, Doris, Maurer, Florian P., Niemann, Stefan, Merker, Matthias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Mechanisms of Resistance
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8218629/ https://www.ncbi.nlm.nih.gov/pubmed/33903103 http://dx.doi.org/10.1128/AAC.02520-20

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