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Microtubule destabilization is a critical checkpoint of chemotaxis and transendothelial migration in melanoma cells but not in T cells

Microtubules (MTs) control cell shape and intracellular cargo transport. The role of MT turnover in the migration of slow-moving cells through endothelial barriers remains unclear. To irreversibly interfere with MT disassembly, we have used the MT-stabilizing agent zampanolide (ZMP) in Β16F10 melano...

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Detalles Bibliográficos
Autores principales: Roncato, Francesco, Regev, Ofer, Yadav, Sandeep Kumar, Alon, Ronen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8218694/
https://www.ncbi.nlm.nih.gov/pubmed/34152257
http://dx.doi.org/10.1080/19336918.2021.1934958