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Microtubule destabilization is a critical checkpoint of chemotaxis and transendothelial migration in melanoma cells but not in T cells
Microtubules (MTs) control cell shape and intracellular cargo transport. The role of MT turnover in the migration of slow-moving cells through endothelial barriers remains unclear. To irreversibly interfere with MT disassembly, we have used the MT-stabilizing agent zampanolide (ZMP) in Β16F10 melano...
Autores principales: | Roncato, Francesco, Regev, Ofer, Yadav, Sandeep Kumar, Alon, Ronen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8218694/ https://www.ncbi.nlm.nih.gov/pubmed/34152257 http://dx.doi.org/10.1080/19336918.2021.1934958 |
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