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Acute arterial ischemia in COVID-19

Since the coronavirus pandemic set in in Spain in March 2020, a noteworthy increase in the incidence of acute limb ischemia (ALI) has been observed. It has been recently discovered that SARS-CoV 2 may lead to ALI secondary to arterial thrombosis. Elevation of D-dimer (DD) in patients with coronaviru...

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Autores principales: Maqueda Ara, Silvia, Ballesteros Pomar, Marta, Sanz Pastor, Nuria, Nogal Arias, Cristina, Del Barrio Fernández, Marcos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV) 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8218827/
https://www.ncbi.nlm.nih.gov/pubmed/34211545
http://dx.doi.org/10.1590/1677-5449.210022
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author Maqueda Ara, Silvia
Ballesteros Pomar, Marta
Sanz Pastor, Nuria
Nogal Arias, Cristina
Del Barrio Fernández, Marcos
author_facet Maqueda Ara, Silvia
Ballesteros Pomar, Marta
Sanz Pastor, Nuria
Nogal Arias, Cristina
Del Barrio Fernández, Marcos
author_sort Maqueda Ara, Silvia
collection PubMed
description Since the coronavirus pandemic set in in Spain in March 2020, a noteworthy increase in the incidence of acute limb ischemia (ALI) has been observed. It has been recently discovered that SARS-CoV 2 may lead to ALI secondary to arterial thrombosis. Elevation of D-dimer (DD) in patients with coronavirus infection (COVID-19) indicates that a hypercoagulable state causes acute arterial thrombosis. A remarkably high DD elevation has been reported to be a poor prognosis factor in COVID-19. The ways in which SARS-CoV 2 results in arterial thrombosis may be multiple. On the other hand, surgical revascularization for ALI is associated with poor outcomes in COVID-19 patients, probably in relation to hypercoagulability. Here, we describe two ALI cases in patients who required urgent surgical treatment for limb salvage and were positive for the novel coronavirus infection (COVID 19).
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spelling pubmed-82188272021-06-30 Acute arterial ischemia in COVID-19 Maqueda Ara, Silvia Ballesteros Pomar, Marta Sanz Pastor, Nuria Nogal Arias, Cristina Del Barrio Fernández, Marcos J Vasc Bras Therapeutic Challenge Since the coronavirus pandemic set in in Spain in March 2020, a noteworthy increase in the incidence of acute limb ischemia (ALI) has been observed. It has been recently discovered that SARS-CoV 2 may lead to ALI secondary to arterial thrombosis. Elevation of D-dimer (DD) in patients with coronavirus infection (COVID-19) indicates that a hypercoagulable state causes acute arterial thrombosis. A remarkably high DD elevation has been reported to be a poor prognosis factor in COVID-19. The ways in which SARS-CoV 2 results in arterial thrombosis may be multiple. On the other hand, surgical revascularization for ALI is associated with poor outcomes in COVID-19 patients, probably in relation to hypercoagulability. Here, we describe two ALI cases in patients who required urgent surgical treatment for limb salvage and were positive for the novel coronavirus infection (COVID 19). Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV) 2021-06-16 /pmc/articles/PMC8218827/ /pubmed/34211545 http://dx.doi.org/10.1590/1677-5449.210022 Text en Copyright© 2021 The authors. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Therapeutic Challenge
Maqueda Ara, Silvia
Ballesteros Pomar, Marta
Sanz Pastor, Nuria
Nogal Arias, Cristina
Del Barrio Fernández, Marcos
Acute arterial ischemia in COVID-19
title Acute arterial ischemia in COVID-19
title_full Acute arterial ischemia in COVID-19
title_fullStr Acute arterial ischemia in COVID-19
title_full_unstemmed Acute arterial ischemia in COVID-19
title_short Acute arterial ischemia in COVID-19
title_sort acute arterial ischemia in covid-19
topic Therapeutic Challenge
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8218827/
https://www.ncbi.nlm.nih.gov/pubmed/34211545
http://dx.doi.org/10.1590/1677-5449.210022
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