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Successful lung transplantation after prone positioning in an ineligible donor: a case report
Atelectasis is a reversible factor in hypoxemia among brain-dead donors. In ineligible donors, prone positioning reverses atelectasis and improves oxygenation. We present a successful lung transplantation after salvaging a previously unviable lung. A 37-year-old woman presented with acute pontine he...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8218964/ https://www.ncbi.nlm.nih.gov/pubmed/34159516 http://dx.doi.org/10.1007/s11748-021-01676-4 |
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author | Son, Eunjeong Jang, Jinook Cho, Woo Hyun Kim, Dohyung Yeo, Hye Ju |
author_facet | Son, Eunjeong Jang, Jinook Cho, Woo Hyun Kim, Dohyung Yeo, Hye Ju |
author_sort | Son, Eunjeong |
collection | PubMed |
description | Atelectasis is a reversible factor in hypoxemia among brain-dead donors. In ineligible donors, prone positioning reverses atelectasis and improves oxygenation. We present a successful lung transplantation after salvaging a previously unviable lung. A 37-year-old woman presented with acute pontine hemorrhage that progressed to brain death. The initial partial pressure of oxygen (PaO(2))/fraction of inspired oxygen (FiO(2)) ratio of the donor’s lung was 342 mmHg. The PaO(2)/FiO(2) ratio dropped to 49 mmHg due to atelectasis. There was no improvement despite recruitment maneuvers, bronchoscopy, and chest percussion. After placing the donor in the prone position for four hours, electrical impedance tomography showed improved atelectasis. The donor did not experience hemodynamic instability. The lung was transplanted into a patient with Kartagener’s syndrome with situs inversus. The surgical procedure was uneventful. He was successfully weaned from the mechanical ventilator on the second-day post-transplantation and was discharged from the hospital after 4 weeks. |
format | Online Article Text |
id | pubmed-8218964 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Springer Singapore |
record_format | MEDLINE/PubMed |
spelling | pubmed-82189642021-06-23 Successful lung transplantation after prone positioning in an ineligible donor: a case report Son, Eunjeong Jang, Jinook Cho, Woo Hyun Kim, Dohyung Yeo, Hye Ju Gen Thorac Cardiovasc Surg Case Report Atelectasis is a reversible factor in hypoxemia among brain-dead donors. In ineligible donors, prone positioning reverses atelectasis and improves oxygenation. We present a successful lung transplantation after salvaging a previously unviable lung. A 37-year-old woman presented with acute pontine hemorrhage that progressed to brain death. The initial partial pressure of oxygen (PaO(2))/fraction of inspired oxygen (FiO(2)) ratio of the donor’s lung was 342 mmHg. The PaO(2)/FiO(2) ratio dropped to 49 mmHg due to atelectasis. There was no improvement despite recruitment maneuvers, bronchoscopy, and chest percussion. After placing the donor in the prone position for four hours, electrical impedance tomography showed improved atelectasis. The donor did not experience hemodynamic instability. The lung was transplanted into a patient with Kartagener’s syndrome with situs inversus. The surgical procedure was uneventful. He was successfully weaned from the mechanical ventilator on the second-day post-transplantation and was discharged from the hospital after 4 weeks. Springer Singapore 2021-06-22 2021 /pmc/articles/PMC8218964/ /pubmed/34159516 http://dx.doi.org/10.1007/s11748-021-01676-4 Text en © The Japanese Association for Thoracic Surgery 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Case Report Son, Eunjeong Jang, Jinook Cho, Woo Hyun Kim, Dohyung Yeo, Hye Ju Successful lung transplantation after prone positioning in an ineligible donor: a case report |
title | Successful lung transplantation after prone positioning in an ineligible donor: a case report |
title_full | Successful lung transplantation after prone positioning in an ineligible donor: a case report |
title_fullStr | Successful lung transplantation after prone positioning in an ineligible donor: a case report |
title_full_unstemmed | Successful lung transplantation after prone positioning in an ineligible donor: a case report |
title_short | Successful lung transplantation after prone positioning in an ineligible donor: a case report |
title_sort | successful lung transplantation after prone positioning in an ineligible donor: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8218964/ https://www.ncbi.nlm.nih.gov/pubmed/34159516 http://dx.doi.org/10.1007/s11748-021-01676-4 |
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