Cargando…
A549 in-silico 1.0: A first computational model to simulate cell cycle dependent ion current modulation in the human lung adenocarcinoma
Lung cancer is still a leading cause of death worldwide. In recent years, knowledge has been obtained of the mechanisms modulating ion channel kinetics and thus of cell bioelectric properties, which is promising for oncological biomarkers and targets. The complex interplay of channel expression and...
Autores principales: | Langthaler, Sonja, Rienmüller, Theresa, Scheruebel, Susanne, Pelzmann, Brigitte, Shrestha, Niroj, Zorn-Pauly, Klaus, Schreibmayer, Wolfgang, Koff, Andrew, Baumgartner, Christian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219159/ https://www.ncbi.nlm.nih.gov/pubmed/34157016 http://dx.doi.org/10.1371/journal.pcbi.1009091 |
Ejemplares similares
-
Consequences of somatic mutations of GIRK1 detected in primary malign tumors on expression and function of G-protein activated, inwardly rectifying, K(+) channels
por: Pelzmann, Brigitte, et al.
Publicado: (2022) -
GIRK1 triggers multiple cancer-related pathways in the benign mammary epithelial cell line MCF10A
por: Schratter, Gebhard, et al.
Publicado: (2019) -
Sinoatrial Beat to Beat Variability Assessed by Contraction Strength in Addition to the Interbeat Interval
por: Ahammer, Helmut, et al.
Publicado: (2018) -
Ion Channel Modeling beyond State of the Art: A Comparison with a System Theory-Based Model of the Shaker-Related Voltage-Gated Potassium Channel Kv1.1
por: Langthaler, Sonja, et al.
Publicado: (2022) -
I(f) blocking potency of ivabradine is preserved under elevated endotoxin levels in human atrial myocytes
por: Scheruebel, Susanne, et al.
Publicado: (2014)