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Predicting Lung Deposition of Extrafine Inhaled Corticosteroid-Containing Fixed Combinations in Patients with Chronic Obstructive Pulmonary Disease Using Functional Respiratory Imaging: An In Silico Study
Background: Functional respiratory imaging (FRI) is a computational fluid dynamics-based technique using three-dimensional models of human lungs and formulation profiles to simulate aerosol deposition. Methods: FRI was used to evaluate lung deposition of extrafine beclomethasone dipropionate (BDP)/f...
Autores principales: | Usmani, Omar S., Mignot, Benjamin, Kendall, Irvin, Maria, Roberta De, Cocconi, Daniela, Georges, George, Scichilone, Nicola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc., publishers
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219200/ https://www.ncbi.nlm.nih.gov/pubmed/33052749 http://dx.doi.org/10.1089/jamp.2020.1601 |
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