Tracking break induced replication reveals its stalling at roadblocks

Break-induced replication (BIR) repairs one-ended double strand breaks (DSBs) similar to those formed by replication collapse or telomere erosion, and it has been implicated in the initiation of genome instability in cancer and other human disease(1,2). Previous studies have defined the enzymes requ...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Liping, Yan, Zhenxin, Osia, Beth A, Twarowski, Jerzy, Sun, Luyang, Kramara, Juraj, Lee, Rosemary, Kumar, Sandeep, Elango, Rajula, Li, Hanzeng, Dang, Weiwei, Ira, Grzegorz, Malkova, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219245/
https://www.ncbi.nlm.nih.gov/pubmed/33473214
http://dx.doi.org/10.1038/s41586-020-03172-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219245/
https://www.ncbi.nlm.nih.gov/pubmed/33473214
http://dx.doi.org/10.1038/s41586-020-03172-w

Ejemplares similares