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Tracking break induced replication reveals its stalling at roadblocks
Break-induced replication (BIR) repairs one-ended double strand breaks (DSBs) similar to those formed by replication collapse or telomere erosion, and it has been implicated in the initiation of genome instability in cancer and other human disease(1,2). Previous studies have defined the enzymes requ...
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219245/ https://www.ncbi.nlm.nih.gov/pubmed/33473214 http://dx.doi.org/10.1038/s41586-020-03172-w |