Cargando…

MicroRNA-9-3p Aggravates Cerebral Ischemia/Reperfusion Injury by Targeting Fibroblast Growth Factor 19 (FGF19) to Inactivate GSK-3β/Nrf2/ARE Signaling

PURPOSE: MicroRNAs (miRNAs) are emerging as essential regulators in the development of cerebral ischemia/reperfusion (I/R) injury. This study aimed to explore the regulation of miR-9-3p on FGF19-GSK-3β/Nrf2/ARE signaling in cerebral I/R injury. MATERIALS AND METHODS: A mouse model with I/R injury wa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Yadong, Yang, Lin, Bo, Chu, Zhang, Xianjing, Zhang, Junli, Li, Yun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219303/ https://www.ncbi.nlm.nih.gov/pubmed/34177264 http://dx.doi.org/10.2147/NDT.S290237

Ejemplares similares

GSK-3β downregulates Nrf2 in cultured cortical neurons and in a rat model of cerebral ischemia-reperfusion
por: Chen, Xi, et al.
Publicado: (2016)

E3 Ubiquitin Ligase FBXO3 Drives Neuroinflammation to Aggravate Cerebral Ischemia/Reperfusion Injury
por: Gao, Yu, et al.
Publicado: (2022)

Activation of AK005401 aggravates acute ischemia/reperfusion mediated hippocampal injury by directly targeting YY1/FGF21
por: Wan, Hongzhi, et al.
Publicado: (2019)

GSK3β Exacerbates Myocardial Ischemia/Reperfusion Injury by Inhibiting Myc
por: Wen, Cong, et al.
Publicado: (2022)

The Role of Nrf2 in Relieving Cerebral Ischemia-Reperfusion Injury
por: Sun, Yu, et al.
Publicado: (2023)

miR-328-3p, a Predictor of Stroke, Aggravates the Cerebral Ischemia-Reperfusion Injury
por: Wang, Shun, et al.
Publicado: (2021)

Zinc accumulation aggravates cerebral ischemia/reperfusion injury by promoting inflammation
por: Li, Wei, et al.
Publicado: (2023)

Gsk3β regulates the resolution of liver ischemia/reperfusion injury via MerTK
por: Zhang, Hanwen, et al.
Publicado: (2023)

Correction for: Activation of AK005401 aggravates acute ischemia/reperfusion mediated hippocampal injury by directly targeting YY1/FGF21
por: Wan, Hongzhi, et al.
Publicado: (2019)

Oleanolic Acid Alleviates Cerebral Ischemia/Reperfusion Injury via Regulation of the GSK-3β/HO-1 Signaling Pathway
por: Lin, Kaili, et al.
Publicado: (2021)

Brite Adipocyte FGF21 Attenuates Cardiac Ischemia/Reperfusion Injury in Rat Hearts by Modulating NRF2
por: Moon, Hanbyeol, et al.
Publicado: (2022)

Protective effect of butin against ischemia/reperfusion-induced myocardial injury in diabetic mice: involvement of the AMPK/GSK-3β/Nrf2 signaling pathway
por: Duan, Jialin, et al.
Publicado: (2017)

Diabetes Worsens Ischemia-Reperfusion Brain Injury in Rats Through GSK-3β
por: Liu, Hua, et al.
Publicado: (2015)

Fatty Acid-Binding Proteins Aggravate Cerebral Ischemia-Reperfusion Injury in Mice
por: Guo, Qingyun, et al.
Publicado: (2021)

Ischemic Postconditioning Alleviates Intestinal Ischemia-Reperfusion Injury by Enhancing Autophagy and Suppressing Oxidative Stress through the Akt/GSK-3β/Nrf2 Pathway in Mice
por: Chen, Rong, et al.
Publicado: (2020)

MicroRNA-489-3p aggravates neuronal apoptosis and oxidative stress after cerebral ischemia-reperfusion injury
por: Song, LiGuo, et al.
Publicado: (2022)

MicroRNA-670 aggravates cerebral ischemia/reperfusion injury via the Yap pathway
por: Yu, Shi-Jia, et al.
Publicado: (2020)

Long non-coding RNA-ROR aggravates myocardial ischemia/reperfusion injury
por: Zhang, Weiwei, et al.
Publicado: (2018)

Activated PKB/GSK-3β synergizes with PKC-δ signaling in attenuating myocardial ischemia/reperfusion injury via potentiation of NRF2 activity: Therapeutic efficacy of dihydrotanshinone-I
por: Zeng, Hao, et al.
Publicado: (2021)

NLRP3 Inflammasome Activation-Mediated Pyroptosis Aggravates Myocardial Ischemia/Reperfusion Injury in Diabetic Rats
por: Qiu, Zhen, et al.
Publicado: (2017)

Aging aggravated liver ischemia and reperfusion injury by promoting STING‐mediated NLRP3 activation in macrophages
por: Zhong, Weizhe, et al.
Publicado: (2020)

GSK-3β as a target for protection against transient cerebral ischemia
por: Wang, Wei, et al.
Publicado: (2017)

Pharmacological postconditioning with atorvastatin calcium attenuates myocardial ischemia/reperfusion injury in diabetic rats by phosphorylating GSK3β
por: Chen, Linyan, et al.
Publicado: (2017)

Ubiquitin-specific protease 11 Aggravates Ischemia-reperfusion-induced Cardiomyocyte Pyroptosis and Injury by Promoting TRAF3 Deubiquitination
por: Zhang, Yunfei, et al.
Publicado: (2023)

Kaempferide Protects against Myocardial Ischemia/Reperfusion Injury through Activation of the PI3K/Akt/GSK-3β Pathway
por: Wang, Dong, et al.
Publicado: (2017)

Electroacupuncture Pretreatment Alleviates Cerebral Ischemia-Reperfusion Injury by Increasing GSK-3β Phosphorylation Level via Adenosine A1 Receptor
por: Geng, Wujun, et al.
Publicado: (2020)

Osteopontin deficiency aggravates hepatic injury induced by ischemia–reperfusion in mice
por: Patouraux, S, et al.
Publicado: (2014)

Deficiency of anti-inflammatory cytokine IL-4 leads to neural hyperexcitability and aggravates cerebral ischemia–reperfusion injury
por: Chen, Xiaoling, et al.
Publicado: (2020)

Novel GSK-3β Inhibitor Neopetroside A Protects Against Murine Myocardial Ischemia/Reperfusion Injury
por: Kim, Hyoung Kyu, et al.
Publicado: (2022)

Pin1 aggravates renal injury induced by ischemia and reperfusion in rats via Nrf2/HO-1 mediated endoplasmic reticulum stress
por: Yu, Honglin, et al.
Publicado: (2022)

MiR-149 Aggravates Pyroptosis in Myocardial Ischemia-Reperfusion Damage via Silencing FoxO3
por: Lin, Jie, et al.
Publicado: (2019)

miR-10a overexpression aggravates renal ischemia–reperfusion injury associated with decreased PIK3CA expression
por: Xu, Dongsheng, et al.
Publicado: (2020)

Astaxanthin alleviates spinal cord ischemia-reperfusion injury via activation of PI3K/Akt/GSK-3β pathway in rats
por: Fu, Jian, et al.
Publicado: (2020)

The Cytoprotective Effect of Hyperoside against Oxidative Stress Is Mediated by the Nrf2-ARE Signaling Pathway through GSK-3β Inactivation
por: Xing, Hai-Yan, et al.
Publicado: (2015)

Activation of NLRP3 Inflammasome via Drp1 Overexpression in Kupffer Cells Aggravates Ischemia-reperfusion Injury in Hepatic Steatosis
por: Zhang, Lu, et al.
Publicado: (2023)

Propofol attenuates lung ischemia/reperfusion injury though the involvement of the MALAT1/microRNA-144/GSK3β axis
por: Zhang, Jian-Ping, et al.
Publicado: (2021)

Hyperglycemia Aggravates Hepatic Ischemia Reperfusion Injury by Inducing Chronic Oxidative Stress and Inflammation
por: Zhang, Yihan, et al.
Publicado: (2016)

Homocysteine Aggravates Cortical Neural Cell Injury through Neuronal Autophagy Overactivation following Rat Cerebral Ischemia-Reperfusion
por: Zhao, Yaqian, et al.
Publicado: (2016)

Cell-penetrating peptide TAT-mediated delivery of acidic FGF to retina and protection against ischemia–reperfusion injury in rats
por: Wang, Yi, et al.
Publicado: (2010)

Kukoamine A activates Akt/GSK-3β signaling pathway to inhibit oxidative stress and relieve myocardial ischemia-reperfusion injury
por: Xu, Han, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_t6hj7j7go7icbodelpfim2qe3f