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Giant leiomyosarcoma of the inferior vena cava necessitating extended liver resection: A case report and review of the literature

Leiomyosarcoma of the inferior vena cava (IVC) is a rare malignant tumour of smooth muscle origin. It commonly presents with non-specific symptoms including abdominal pain, distention, and lower extremity edema. Surgical resection with macroscopically clear margins is the only potential curative tre...

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Autores principales: Silverman, Jacob, Pencovich, Niv, Mayer, Chen, Volkov, Alexander, Eshkenazi, Rony, Nachmany, Ido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219390/
https://www.ncbi.nlm.nih.gov/pubmed/34168858
http://dx.doi.org/10.1093/jscr/rjab271
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author Silverman, Jacob
Pencovich, Niv
Mayer, Chen
Volkov, Alexander
Eshkenazi, Rony
Nachmany, Ido
author_facet Silverman, Jacob
Pencovich, Niv
Mayer, Chen
Volkov, Alexander
Eshkenazi, Rony
Nachmany, Ido
author_sort Silverman, Jacob
collection PubMed
description Leiomyosarcoma of the inferior vena cava (IVC) is a rare malignant tumour of smooth muscle origin. It commonly presents with non-specific symptoms including abdominal pain, distention, and lower extremity edema. Surgical resection with macroscopically clear margins is the only potential curative treatment for the disease. Here we present the case of a previously healthy 38-year-old woman with a subacute one-month increase of a four-year slowly progressive right sided abdominal pain and back pain. Imaging revealed a 14.5x12x15cm mass in the right hepatic lobe causing mass effect on adjacent abdominal and retroperitoneal organs, and involving the retrohepatic IVC. En-bloc resection of the right hemi-liver, most of segment four, the caudate lobe, and approximately a 10 cm section of the retrohepatic IVC, along with IVC reconstruction, was performed. Histologic examination revealed the diagnosis of a high grade leiomyosarcoma.
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spelling pubmed-82193902021-06-23 Giant leiomyosarcoma of the inferior vena cava necessitating extended liver resection: A case report and review of the literature Silverman, Jacob Pencovich, Niv Mayer, Chen Volkov, Alexander Eshkenazi, Rony Nachmany, Ido J Surg Case Rep Case Report Leiomyosarcoma of the inferior vena cava (IVC) is a rare malignant tumour of smooth muscle origin. It commonly presents with non-specific symptoms including abdominal pain, distention, and lower extremity edema. Surgical resection with macroscopically clear margins is the only potential curative treatment for the disease. Here we present the case of a previously healthy 38-year-old woman with a subacute one-month increase of a four-year slowly progressive right sided abdominal pain and back pain. Imaging revealed a 14.5x12x15cm mass in the right hepatic lobe causing mass effect on adjacent abdominal and retroperitoneal organs, and involving the retrohepatic IVC. En-bloc resection of the right hemi-liver, most of segment four, the caudate lobe, and approximately a 10 cm section of the retrohepatic IVC, along with IVC reconstruction, was performed. Histologic examination revealed the diagnosis of a high grade leiomyosarcoma. Oxford University Press 2021-06-22 /pmc/articles/PMC8219390/ /pubmed/34168858 http://dx.doi.org/10.1093/jscr/rjab271 Text en Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2021. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Silverman, Jacob
Pencovich, Niv
Mayer, Chen
Volkov, Alexander
Eshkenazi, Rony
Nachmany, Ido
Giant leiomyosarcoma of the inferior vena cava necessitating extended liver resection: A case report and review of the literature
title Giant leiomyosarcoma of the inferior vena cava necessitating extended liver resection: A case report and review of the literature
title_full Giant leiomyosarcoma of the inferior vena cava necessitating extended liver resection: A case report and review of the literature
title_fullStr Giant leiomyosarcoma of the inferior vena cava necessitating extended liver resection: A case report and review of the literature
title_full_unstemmed Giant leiomyosarcoma of the inferior vena cava necessitating extended liver resection: A case report and review of the literature
title_short Giant leiomyosarcoma of the inferior vena cava necessitating extended liver resection: A case report and review of the literature
title_sort giant leiomyosarcoma of the inferior vena cava necessitating extended liver resection: a case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219390/
https://www.ncbi.nlm.nih.gov/pubmed/34168858
http://dx.doi.org/10.1093/jscr/rjab271
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