Switching Cytolytic Nanopores into Antimicrobial Fractal Ruptures by a Single Side Chain Mutation

Disruption of cell membranes is a fundamental host defence response found in virtually all forms of life. The molecular mechanisms vary but generally lead to energetically favored circular nanopores. Here we report an elaborate fractal rupture pattern induced by a single side-chain mutation in ultra...

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Detalles Bibliográficos
Autores principales: Hammond, Katharine, Cipcigan, Flaviu, Al Nahas, Kareem, Losasso, Valeria, Lewis, Helen, Cama, Jehangir, Martelli, Fausto, Simcock, Patrick W, Fletcher, Marcus, Ravi, Jascindra, Stansfeld, Phillip J, Pagliara, Stefano, Hoogenboom, Bart W, Keyser, Ulrich F, Sansom, Mark S P, Crain, Jason, Ryadnov, Maxim G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219408/
https://www.ncbi.nlm.nih.gov/pubmed/33885289
http://dx.doi.org/10.1021/acsnano.1c00218

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