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Child mortality in England during the COVID-19 pandemic
OBJECTIVES: Using the National Child Mortality Database (NCMD), this work aims to investigate and quantify the characteristics of children dying of COVID-19, and to identify any changes in rate of childhood mortality during the pandemic. DESIGN: We compared the characteristics of the children who di...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219479/ https://www.ncbi.nlm.nih.gov/pubmed/34911683 http://dx.doi.org/10.1136/archdischild-2020-320899 |
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author | Odd, David Stoianova, Sylvia Williams, Tom Sleap, Vicky Blair, Peter Fleming, Peter Wolfe, Ingrid Luyt, Karen |
author_facet | Odd, David Stoianova, Sylvia Williams, Tom Sleap, Vicky Blair, Peter Fleming, Peter Wolfe, Ingrid Luyt, Karen |
author_sort | Odd, David |
collection | PubMed |
description | OBJECTIVES: Using the National Child Mortality Database (NCMD), this work aims to investigate and quantify the characteristics of children dying of COVID-19, and to identify any changes in rate of childhood mortality during the pandemic. DESIGN: We compared the characteristics of the children who died in 2020, split by SARS-CoV-2 status. A negative binomial regression model was used to compare mortality rates in lockdown (23 March–28 June), with those children who died in the preceding period (6 January–22 March), as well as a comparable period in 2019. SETTING: England. PARTICIPANTS: Children (0–17 years). MAIN OUTCOME MEASURES: Characteristics and number of the children who died in 2020, split by SARS-CoV-2 status. RESULTS: 1550 deaths of children between 6th of January and 28 June 2020 were notified to the NCMD; 437 of the deaths were linked to SARS-CoV-2 virology records, 25 (5.7%) had a positive PCR result. PCR-positive children were less likely to be white (37.5% vs 69.4%, p=0.003) and were older (12.2 vs 0.7 years, p<0.0006) compared with child deaths without evidence of the virus. All-cause mortality rates were similar during lockdown compared with both the period before lockdown in 2020 (rate ratio (RR) 0.93 (0.84 to 1.02)) and a similar period in 2019 (RR 1.02 (0.92 to 1.13)). CONCLUSIONS: There is little to suggest that there has been excess mortality during the period of lockdown. The apparent higher frequency of SARS-CoV-2-positive tests among children from black, Asian and minority ethnic groups is consistent with findings in adults. Ongoing surveillance is essential as the pandemic continues. |
format | Online Article Text |
id | pubmed-8219479 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-82194792021-06-28 Child mortality in England during the COVID-19 pandemic Odd, David Stoianova, Sylvia Williams, Tom Sleap, Vicky Blair, Peter Fleming, Peter Wolfe, Ingrid Luyt, Karen Arch Dis Child Original Research OBJECTIVES: Using the National Child Mortality Database (NCMD), this work aims to investigate and quantify the characteristics of children dying of COVID-19, and to identify any changes in rate of childhood mortality during the pandemic. DESIGN: We compared the characteristics of the children who died in 2020, split by SARS-CoV-2 status. A negative binomial regression model was used to compare mortality rates in lockdown (23 March–28 June), with those children who died in the preceding period (6 January–22 March), as well as a comparable period in 2019. SETTING: England. PARTICIPANTS: Children (0–17 years). MAIN OUTCOME MEASURES: Characteristics and number of the children who died in 2020, split by SARS-CoV-2 status. RESULTS: 1550 deaths of children between 6th of January and 28 June 2020 were notified to the NCMD; 437 of the deaths were linked to SARS-CoV-2 virology records, 25 (5.7%) had a positive PCR result. PCR-positive children were less likely to be white (37.5% vs 69.4%, p=0.003) and were older (12.2 vs 0.7 years, p<0.0006) compared with child deaths without evidence of the virus. All-cause mortality rates were similar during lockdown compared with both the period before lockdown in 2020 (rate ratio (RR) 0.93 (0.84 to 1.02)) and a similar period in 2019 (RR 1.02 (0.92 to 1.13)). CONCLUSIONS: There is little to suggest that there has been excess mortality during the period of lockdown. The apparent higher frequency of SARS-CoV-2-positive tests among children from black, Asian and minority ethnic groups is consistent with findings in adults. Ongoing surveillance is essential as the pandemic continues. BMJ Publishing Group 2022-01 2021-06-21 /pmc/articles/PMC8219479/ /pubmed/34911683 http://dx.doi.org/10.1136/archdischild-2020-320899 Text en © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) . |
spellingShingle | Original Research Odd, David Stoianova, Sylvia Williams, Tom Sleap, Vicky Blair, Peter Fleming, Peter Wolfe, Ingrid Luyt, Karen Child mortality in England during the COVID-19 pandemic |
title | Child mortality in England during the COVID-19 pandemic |
title_full | Child mortality in England during the COVID-19 pandemic |
title_fullStr | Child mortality in England during the COVID-19 pandemic |
title_full_unstemmed | Child mortality in England during the COVID-19 pandemic |
title_short | Child mortality in England during the COVID-19 pandemic |
title_sort | child mortality in england during the covid-19 pandemic |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219479/ https://www.ncbi.nlm.nih.gov/pubmed/34911683 http://dx.doi.org/10.1136/archdischild-2020-320899 |
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