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Child mortality in England during the COVID-19 pandemic

OBJECTIVES: Using the National Child Mortality Database (NCMD), this work aims to investigate and quantify the characteristics of children dying of COVID-19, and to identify any changes in rate of childhood mortality during the pandemic. DESIGN: We compared the characteristics of the children who di...

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Autores principales: Odd, David, Stoianova, Sylvia, Williams, Tom, Sleap, Vicky, Blair, Peter, Fleming, Peter, Wolfe, Ingrid, Luyt, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219479/
https://www.ncbi.nlm.nih.gov/pubmed/34911683
http://dx.doi.org/10.1136/archdischild-2020-320899
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author Odd, David
Stoianova, Sylvia
Williams, Tom
Sleap, Vicky
Blair, Peter
Fleming, Peter
Wolfe, Ingrid
Luyt, Karen
author_facet Odd, David
Stoianova, Sylvia
Williams, Tom
Sleap, Vicky
Blair, Peter
Fleming, Peter
Wolfe, Ingrid
Luyt, Karen
author_sort Odd, David
collection PubMed
description OBJECTIVES: Using the National Child Mortality Database (NCMD), this work aims to investigate and quantify the characteristics of children dying of COVID-19, and to identify any changes in rate of childhood mortality during the pandemic. DESIGN: We compared the characteristics of the children who died in 2020, split by SARS-CoV-2 status. A negative binomial regression model was used to compare mortality rates in lockdown (23 March–28 June), with those children who died in the preceding period (6 January–22 March), as well as a comparable period in 2019. SETTING: England. PARTICIPANTS: Children (0–17 years). MAIN OUTCOME MEASURES: Characteristics and number of the children who died in 2020, split by SARS-CoV-2 status. RESULTS: 1550 deaths of children between 6th of January and 28 June 2020 were notified to the NCMD; 437 of the deaths were linked to SARS-CoV-2 virology records, 25 (5.7%) had a positive PCR result. PCR-positive children were less likely to be white (37.5% vs 69.4%, p=0.003) and were older (12.2 vs 0.7 years, p<0.0006) compared with child deaths without evidence of the virus. All-cause mortality rates were similar during lockdown compared with both the period before lockdown in 2020 (rate ratio (RR) 0.93 (0.84 to 1.02)) and a similar period in 2019 (RR 1.02 (0.92 to 1.13)). CONCLUSIONS: There is little to suggest that there has been excess mortality during the period of lockdown. The apparent higher frequency of SARS-CoV-2-positive tests among children from black, Asian and minority ethnic groups is consistent with findings in adults. Ongoing surveillance is essential as the pandemic continues.
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spelling pubmed-82194792021-06-28 Child mortality in England during the COVID-19 pandemic Odd, David Stoianova, Sylvia Williams, Tom Sleap, Vicky Blair, Peter Fleming, Peter Wolfe, Ingrid Luyt, Karen Arch Dis Child Original Research OBJECTIVES: Using the National Child Mortality Database (NCMD), this work aims to investigate and quantify the characteristics of children dying of COVID-19, and to identify any changes in rate of childhood mortality during the pandemic. DESIGN: We compared the characteristics of the children who died in 2020, split by SARS-CoV-2 status. A negative binomial regression model was used to compare mortality rates in lockdown (23 March–28 June), with those children who died in the preceding period (6 January–22 March), as well as a comparable period in 2019. SETTING: England. PARTICIPANTS: Children (0–17 years). MAIN OUTCOME MEASURES: Characteristics and number of the children who died in 2020, split by SARS-CoV-2 status. RESULTS: 1550 deaths of children between 6th of January and 28 June 2020 were notified to the NCMD; 437 of the deaths were linked to SARS-CoV-2 virology records, 25 (5.7%) had a positive PCR result. PCR-positive children were less likely to be white (37.5% vs 69.4%, p=0.003) and were older (12.2 vs 0.7 years, p<0.0006) compared with child deaths without evidence of the virus. All-cause mortality rates were similar during lockdown compared with both the period before lockdown in 2020 (rate ratio (RR) 0.93 (0.84 to 1.02)) and a similar period in 2019 (RR 1.02 (0.92 to 1.13)). CONCLUSIONS: There is little to suggest that there has been excess mortality during the period of lockdown. The apparent higher frequency of SARS-CoV-2-positive tests among children from black, Asian and minority ethnic groups is consistent with findings in adults. Ongoing surveillance is essential as the pandemic continues. BMJ Publishing Group 2022-01 2021-06-21 /pmc/articles/PMC8219479/ /pubmed/34911683 http://dx.doi.org/10.1136/archdischild-2020-320899 Text en © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Original Research
Odd, David
Stoianova, Sylvia
Williams, Tom
Sleap, Vicky
Blair, Peter
Fleming, Peter
Wolfe, Ingrid
Luyt, Karen
Child mortality in England during the COVID-19 pandemic
title Child mortality in England during the COVID-19 pandemic
title_full Child mortality in England during the COVID-19 pandemic
title_fullStr Child mortality in England during the COVID-19 pandemic
title_full_unstemmed Child mortality in England during the COVID-19 pandemic
title_short Child mortality in England during the COVID-19 pandemic
title_sort child mortality in england during the covid-19 pandemic
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219479/
https://www.ncbi.nlm.nih.gov/pubmed/34911683
http://dx.doi.org/10.1136/archdischild-2020-320899
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