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Comprehensive identification of transposable element insertions using multiple sequencing technologies

Transposable elements (TEs) help shape the structure and function of the human genome. When inserted into some locations, TEs may disrupt gene regulation and cause diseases. Here, we present xTea (x-Transposable element analyzer), a tool for identifying TE insertions in whole-genome sequencing data....

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Detalles Bibliográficos
Autores principales: Chu, Chong, Borges-Monroy, Rebeca, Viswanadham, Vinayak V., Lee, Soohyun, Li, Heng, Lee, Eunjung Alice, Park, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219666/
https://www.ncbi.nlm.nih.gov/pubmed/34158502
http://dx.doi.org/10.1038/s41467-021-24041-8