Direct activation of the proton channel by albumin leads to human sperm capacitation and sustained release of inflammatory mediators by neutrophils

Human voltage-gated proton channels (hHv1) extrude protons from cells to compensate for charge and osmotic imbalances due metabolism, normalizing intracellular pH and regulating protein function. Human albumin (Alb), present at various levels throughout the body, regulates oncotic pressure and trans...

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Detalles Bibliográficos
Autores principales: Zhao, Ruiming, Dai, Hui, Arias, Rodolfo J., De Blas, Gerardo A., Orta, Gerardo, Pavarotti, Martín A., Shen, Rong, Perozo, Eduardo, Mayorga, Luis S., Darszon, Alberto, Goldstein, Steve A. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219737/
https://www.ncbi.nlm.nih.gov/pubmed/34158477
http://dx.doi.org/10.1038/s41467-021-24145-1

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