The combined action of CTCF and its testis-specific paralog BORIS is essential for spermatogenesis

CTCF is a key organizer of the 3D genome. Its specialized paralog, BORIS, heterodimerizes with CTCF but is expressed only in male germ cells and in cancer states. Unexpectedly, BORIS-null mice have only minimal germ cell defects. To understand the CTCF-BORIS relationship, mouse models with varied CT...

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Detalles Bibliográficos
Autores principales: Rivero-Hinojosa, Samuel, Pugacheva, Elena M., Kang, Sungyun, Méndez-Catalá, Claudia Fabiola, Kovalchuk, Alexander L., Strunnikov, Alexander V., Loukinov, Dmitri, Lee, Jeannie T., Lobanenkov, Victor V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219828/
https://www.ncbi.nlm.nih.gov/pubmed/34158481
http://dx.doi.org/10.1038/s41467-021-24140-6

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