Oncolytic H-1 parvovirus binds to sialic acid on laminins for cell attachment and entry

H-1 parvovirus (H-1PV) is a promising anticancer therapy. However, in-depth understanding of its life cycle, including the host cell factors needed for infectivity and oncolysis, is lacking. This understanding may guide the rational design of combination strategies, aid development of more effective...

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Detalles Bibliográficos
Autores principales: Kulkarni, Amit, Ferreira, Tiago, Bretscher, Clemens, Grewenig, Annabel, El-Andaloussi, Nazim, Bonifati, Serena, Marttila, Tiina, Palissot, Valérie, Hossain, Jubayer A., Azuaje, Francisco, Miletic, Hrvoje, Ystaas, Lars A. R., Golebiewska, Anna, Niclou, Simone P., Roeth, Ralf, Niesler, Beate, Weiss, Amélie, Brino, Laurent, Marchini, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219832/
https://www.ncbi.nlm.nih.gov/pubmed/34158478
http://dx.doi.org/10.1038/s41467-021-24034-7

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