The ATF6β-calreticulin axis promotes neuronal survival under endoplasmic reticulum stress and excitotoxicity

While ATF6α plays a central role in the endoplasmic reticulum (ER) stress response, the function of its paralogue ATF6β remains elusive, especially in the central nervous system (CNS). Here, we demonstrate that ATF6β is highly expressed in the hippocampus of the brain, and specifically regulates the...

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Detalles Bibliográficos
Autores principales: Nguyen, Dinh Thi, Le, Thuong Manh, Hattori, Tsuyoshi, Takarada-Iemata, Mika, Ishii, Hiroshi, Roboon, Jureepon, Tamatani, Takashi, Kannon, Takayuki, Hosomichi, Kazuyoshi, Tajima, Atsushi, Taniuchi, Shusuke, Miyake, Masato, Oyadomari, Seiichi, Tanaka, Takashi, Kato, Nobuo, Saito, Shunsuke, Mori, Kazutoshi, Hori, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219835/
https://www.ncbi.nlm.nih.gov/pubmed/34158584
http://dx.doi.org/10.1038/s41598-021-92529-w

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