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Relevance of Brain (18)F-FDG PET Imaging in Probable Seronegative Encephalitis With Catatonia: A Case Report

Autoimmune encephalitis (AIE) is a rare, severe, and rapidly progressive encephalopathy, and its diagnosis is challenging, especially in adolescent populations when the presentation is mainly psychiatric. Currently, cerebral 18-fluorodeoxyglucose positron emission tomography ((18)F-FDG-PET) imaging...

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Detalles Bibliográficos
Autores principales: Guetta, Michaël, Kas, Aurélie, Aouidad, Aveline, Soret, Marine, Allenbach, Yves, Bordonné, Manon, Oppetit, Alice, Raffin, Marie, Psimaras, Dimitri, Cohen, David, Consoli, Angèle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219867/
https://www.ncbi.nlm.nih.gov/pubmed/34177668
http://dx.doi.org/10.3389/fpsyt.2021.685711
Descripción
Sumario:Autoimmune encephalitis (AIE) is a rare, severe, and rapidly progressive encephalopathy, and its diagnosis is challenging, especially in adolescent populations when the presentation is mainly psychiatric. Currently, cerebral 18-fluorodeoxyglucose positron emission tomography ((18)F-FDG-PET) imaging is not included in the diagnosis algorithm. We describe a 16-year-old patient with probable seronegative encephalitis with catatonia for which several cerebral PET scans were relevant and helpful for diagnosis, treatment decision making, and follow-up monitoring. The patient recovered after 2 years of treatment with etiologic treatment of AIE and treatment of catatonia. This case suggests a more systematic assessment of the clinical relevance of (18)F-FDG-PET imaging in probable seronegative AIE.