Cargando…

Nrf2 Down-Regulation by Camptothecin Favors Inhibiting Invasion, Metastasis and Angiogenesis in Hepatocellular Carcinoma

Higher oxidant stress capacity could promote invasion and metastasis. A previous study showed hepatocellular carcinoma (HCC) expressed more Nrf2 than para-carcinoma tissue. The chemotherapeutics such as epirubicin (EPI) could increase Nrf2 expression, while Camptothecin (CPT) could inhibit tumor gro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Qian, Zhao, Shanshan, Meng, Fanguang, Wang, Hankang, Sun, Liwei, Li, Guijie, Gao, Feng, Chen, Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8219964/ https://www.ncbi.nlm.nih.gov/pubmed/34178646 http://dx.doi.org/10.3389/fonc.2021.661157

Ejemplares similares

Camptothecin improves sorafenib sensitivity by inhibiting Nrf2‑ARE pathway in hepatocellular carcinoma
por: Sun, Liwei, et al.
Publicado: (2023)

Experimental study of camptothecin combined with drug-eluting bead transarterial chemoembolization in the rabbit VX2 liver tumor model
por: Meng, Fanguang, et al.
Publicado: (2022)

Lenvatinib plus transarterial chemoembolization with or without immune checkpoint inhibitors for unresectable hepatocellular carcinoma: A review
por: Sun, Liwei, et al.
Publicado: (2022)

Camptothecin suppresses NRF2–ARE activity and sensitises hepatocellular carcinoma cells to anticancer drugs
por: Chen, Feng, et al.
Publicado: (2017)

Correction: Camptothecin suppresses NRF2–ARE activity and sensitises hepatocellular carcinoma cells to anticancer drugs
por: Chen, Feng, et al.
Publicado: (2019)

Camptothecin Sensitizes Hepatocellular Carcinoma Cells to Sorafenib- Induced Ferroptosis Via Suppression of Nrf2
por: Elkateb, Ahmed S., et al.
Publicado: (2023)

Editorial: Angiogenesis and tumor metastasis
por: Zhang, Qiang-Zhe, et al.
Publicado: (2023)

Effect of Huaier on Melanoma Invasion, Metastasis, and Angiogenesis
por: Su, Dongqiang, et al.
Publicado: (2020)

Injectable Hydrogel System for Camptothecin Initiated Nanocatalytic Tumor Therapy With High Performance
por: Wang, Shuntao, et al.
Publicado: (2022)

YMO1 suppresses invasion and metastasis by inhibiting RhoC signaling and predicts favorable prognosis in hepatocellular carcinoma
por: Chang, Rui-Min, et al.
Publicado: (2016)

PA28α/β Promote Breast Cancer Cell Invasion and Metastasis via Down-Regulation of CDK15
por: Li, Shengnan, et al.
Publicado: (2019)

Down-Regulation of Collagen Hydroxylation in Colorectal Liver Metastasis
por: van Huizen, Nick A., et al.
Publicado: (2020)

From Tumor Cells to Endothelium and Gut Microbiome: A Complex Interaction Favoring the Metastasis Cascade
por: Abdel Sater, Ali H., et al.
Publicado: (2022)

Antidiabetic Agent DPP-4i Facilitates Murine Breast Cancer Metastasis by Oncogenic ROS-NRF2-HO-1 Axis via a Positive NRF2-HO-1 Feedback Loop
por: Li, Rui, et al.
Publicado: (2021)

A rare case of pituitary metastasis from hepatocellular carcinoma: case report and literature review
por: Cheng, Yuanchen, et al.
Publicado: (2023)

Corona enhancement combined with microvascular invasion for prognosis prediction of macrotrabecular-massive hepatocellular carcinoma subtype
por: Yang, Lili, et al.
Publicado: (2023)

Pituitary metastasis of hepatocellular carcinoma as the initial presentations: a case report and review of the literature
por: He, Qiang, et al.
Publicado: (2023)

YY1 Promotes Endothelial Cell-Dependent Tumor Angiogenesis in Hepatocellular Carcinoma by Transcriptionally Activating VEGFA
por: Yang, Wendong, et al.
Publicado: (2019)

Efficacy of Cyproheptadine Monotherapy in Hepatocellular Carcinoma With Bone Metastasis: A Case Report
por: Feng, Yu-Min, et al.
Publicado: (2021)

Dihydrocapsaicin Inhibits Cell Proliferation and Metastasis in Melanoma via Down-regulating β-Catenin Pathway
por: Shi, Shaomin, et al.
Publicado: (2021)

Transarterial chemoembolization for advanced hepatocellular carcinoma without macrovascular invasion or extrahepatic metastasis: analysis of factors prognostic of clinical outcomes
por: Kim, Ji Hoon, et al.
Publicado: (2023)

High Expression of PAMR1 Predicts Favorable Prognosis and Inhibits Proliferation, Invasion, and Migration in Cervical Cancer
por: Yang, Rui, et al.
Publicado: (2021)

Mitochondria-Targeted Delivery of Camptothecin Based on HPMA Copolymer for Metastasis Suppression
por: Yi, Xiaoli, et al.
Publicado: (2022)

Corrigendum: YY1 Promotes Endothelial Cell-Dependent Tumor Angiogenesis in Hepatocellular Carcinoma by Transcriptionally Activating VEGFA
por: Yang, Wendong, et al.
Publicado: (2022)

Emerging Perspectives of Bone Metastasis in Hepatocellular Carcinoma
por: Yuan, Xiaofeng, et al.
Publicado: (2022)

Corrigendum: Dihydrocapsaicin inhibits cell proliferation and metastasis in melanoma via down-regulating β-catenin pathway
por: Shi, Shaomin, et al.
Publicado: (2022)

Case Report: Favorable Response to the Tyrosine Kinase Inhibitor Apatinib in Recurrent Merkel Cell Carcinoma
por: Feng, Yiyi, et al.
Publicado: (2021)

DMF Activates NRF2 to Inhibit the Pro-Invasion Ability of TAMs in Breast Cancer
por: Li, Ying, et al.
Publicado: (2021)

MAPK-RAP1A Signaling Enriched in Hepatocellular Carcinoma Is Associated With Favorable Tumor-Infiltrating Immune Cells and Clinical Prognosis
por: Li, Hailin, et al.
Publicado: (2021)

An Exceptionally Favorable Response to Etoposide and Cisplatin
por: Valecha, Gautam, et al.
Publicado: (2015)

Favorable Response of Metastatic Hepatocellular Carcinoma to Treatment with Trans-arterial Radioembolization Followed by Sorafenib and Nivolumab
por: Adcock, Charles S, et al.
Publicado: (2019)

Down Regulation of the Expression of ELMO3 by COX2 Inhibitor Suppresses Tumor Growth and Metastasis in Non-Small-Cell Lung Cancer
por: Pan, Cailong, et al.
Publicado: (2019)

Exosomal circRNA-100338 promotes hepatocellular carcinoma metastasis via enhancing invasiveness and angiogenesis
por: Huang, Xiu-Yan, et al.
Publicado: (2020)

TIPE1 Inhibits Breast Cancer Proliferation by Downregulating ERK Phosphorylation and Predicts a Favorable Prognosis
por: Hu, Wei, et al.
Publicado: (2019)

VISTA Expression on Immune Cells Correlates With Favorable Prognosis in Patients With Triple-Negative Breast Cancer
por: Cao, Xi, et al.
Publicado: (2021)

IRF6 Is Directly Regulated by ZEB1 and ELF3, and Predicts a Favorable Prognosis in Gastric Cancer
por: Li, Dandan, et al.
Publicado: (2019)

FAM21C Promotes Hepatocellular Carcinoma Invasion and Metastasis by Driving Actin Cytoskeleton Remodeling via Inhibiting Capping Ability of CAPZA1
por: Lu, Yao, et al.
Publicado: (2022)

Beyond Hepatocellular Carcinoma and Colorectal Metastasis: The Expanding Applications of Radioembolization
por: Zurkiya, Omar, et al.
Publicado: (2014)

Effects of the combination of camptothecin and doxorubicin or etoposide on rat glioma cells and camptothecin-resistant variants
por: Pavillard, V, et al.
Publicado: (2001)

Characterization of DNA Topoisomerase-1 in Spodoptera exigua for Toxicity Evaluation of Camptothecin and Hydoxy-Camptothecin
por: Zhang, Lan, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_5et1t31uhdc23thamigr4as0ga