Deletion of ER-retention motif on SARS-CoV-2 spike protein reduces cell hybrid during cell–cell fusion

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BACKGROUND: The novel SARS-CoV-2 has quickly become a global pandemic since the first reported case in December 2019, with the virus infecting millions of people to date. The spike (S) protein of the SARS-CoV-2 virus plays a key role in binding to angiotensin-converting enzyme 2 (ACE2), a host cell...

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Detalles Bibliográficos
Autores principales: Wang, Xuening, Chen, Chih-Hsiung, Badeti, Saiaditya, Cho, Jong Hyun, Naghizadeh, Alireza, Wang, Ziren, Liu, Dongfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220125/
https://www.ncbi.nlm.nih.gov/pubmed/34162440
http://dx.doi.org/10.1186/s13578-021-00626-0
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