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Methodology for risk assessment of COVID-19 pandemic propagation
This paper proposes a methodology to perform risk analysis of the virus spread. It is based on the coupling between CFD modelling of bioaerosol dispersion to the calculation of probability of contact events. CFD model of near-field sneeze droplets dispersion is developed to build the SARS-CoV-2 effe...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220128/ https://www.ncbi.nlm.nih.gov/pubmed/34177131 http://dx.doi.org/10.1016/j.jlp.2021.104584 |
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author | Portarapillo, Maria Di Benedetto, Almerinda |
author_facet | Portarapillo, Maria Di Benedetto, Almerinda |
author_sort | Portarapillo, Maria |
collection | PubMed |
description | This paper proposes a methodology to perform risk analysis of the virus spread. It is based on the coupling between CFD modelling of bioaerosol dispersion to the calculation of probability of contact events. CFD model of near-field sneeze droplets dispersion is developed to build the SARS-CoV-2 effect zones and to adequately capture the safe distance. The most shared classification of droplets size distribution of sneezes was used. Droplets were modeled through additive heating/evaporation/boiling laws and their impact on the continuous phase was examined. Larger droplets move behind the droplet nuclei front and exhibit greater vertical drop due to the effect of gravity. CFD simulations provided the iso-risk curves extension (i.e., the maximum distance as well as the angle) enclosed by the incident outcome effect zone. To calculate the risk indexes, a fault tree was developed and the probability of transmission assuming as of the top event “COVID-19 infection” was calculated starting from the virus spread curve, as main base case. Four phases of virus spread evolution were identified: initiation, propagation, generalised propagation and termination. For each phase, the maximum allowable close contact was computed, being fixed the values of the acceptable risk index. In particular, it was found that during the propagation case, the maximum allowable close contacts is two, suggesting that at this point lockdown should be activated. The here developed methodology could drive policy containment design to curb spread COVID-19 infection. |
format | Online Article Text |
id | pubmed-8220128 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-82201282021-06-23 Methodology for risk assessment of COVID-19 pandemic propagation Portarapillo, Maria Di Benedetto, Almerinda J Loss Prev Process Ind Article This paper proposes a methodology to perform risk analysis of the virus spread. It is based on the coupling between CFD modelling of bioaerosol dispersion to the calculation of probability of contact events. CFD model of near-field sneeze droplets dispersion is developed to build the SARS-CoV-2 effect zones and to adequately capture the safe distance. The most shared classification of droplets size distribution of sneezes was used. Droplets were modeled through additive heating/evaporation/boiling laws and their impact on the continuous phase was examined. Larger droplets move behind the droplet nuclei front and exhibit greater vertical drop due to the effect of gravity. CFD simulations provided the iso-risk curves extension (i.e., the maximum distance as well as the angle) enclosed by the incident outcome effect zone. To calculate the risk indexes, a fault tree was developed and the probability of transmission assuming as of the top event “COVID-19 infection” was calculated starting from the virus spread curve, as main base case. Four phases of virus spread evolution were identified: initiation, propagation, generalised propagation and termination. For each phase, the maximum allowable close contact was computed, being fixed the values of the acceptable risk index. In particular, it was found that during the propagation case, the maximum allowable close contacts is two, suggesting that at this point lockdown should be activated. The here developed methodology could drive policy containment design to curb spread COVID-19 infection. Elsevier Ltd. 2021-09 2021-06-23 /pmc/articles/PMC8220128/ /pubmed/34177131 http://dx.doi.org/10.1016/j.jlp.2021.104584 Text en © 2021 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Portarapillo, Maria Di Benedetto, Almerinda Methodology for risk assessment of COVID-19 pandemic propagation |
title | Methodology for risk assessment of COVID-19 pandemic propagation |
title_full | Methodology for risk assessment of COVID-19 pandemic propagation |
title_fullStr | Methodology for risk assessment of COVID-19 pandemic propagation |
title_full_unstemmed | Methodology for risk assessment of COVID-19 pandemic propagation |
title_short | Methodology for risk assessment of COVID-19 pandemic propagation |
title_sort | methodology for risk assessment of covid-19 pandemic propagation |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220128/ https://www.ncbi.nlm.nih.gov/pubmed/34177131 http://dx.doi.org/10.1016/j.jlp.2021.104584 |
work_keys_str_mv | AT portarapillomaria methodologyforriskassessmentofcovid19pandemicpropagation AT dibenedettoalmerinda methodologyforriskassessmentofcovid19pandemicpropagation |