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Oral fexinidazole for stage 1 or early stage 2 African Trypanosoma brucei gambiense trypanosomiasis: a prospective, multicentre, open-label, cohort study

BACKGROUND: Staging and treatment of human African trypanosomiasis caused by Trypanosoma brucei gambiense (g-HAT) required lumbar puncture to assess cerebrospinal fluid (CSF) and intravenous drugs that cross the blood–brain barrier for late-stage infection. These procedures are inconvenient in rural...

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Detalles Bibliográficos
Autores principales: Kande Betu Ku Mesu, Victor, Mutombo Kalonji, Wilfried, Bardonneau, Clélia, Valverde Mordt, Olaf, Ngolo Tete, Digas, Blesson, Séverine, Simon, François, Delhomme, Sophie, Bernhard, Sonja, Mahenzi Mbembo, Hélène, Mpia Moke, Christian, Lumeya Vuvu, Steven, Mudji E'kitiak, Junior, Akwaso Masa, Felix, Mukendi Ilunga, Melchias, Mpoyi Muamba Nzambi, Dieudonné, Mayala Malu, Tim, Kapongo Tshilumbwa, Serge, Botalema Bolengi, Franck, Nkieri Matsho, Mathieu, Lumbala, Crispin, Scherrer, Bruno, Strub-Wourgaft, Nathalie, Tarral, Antoine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220131/
https://www.ncbi.nlm.nih.gov/pubmed/34143998
http://dx.doi.org/10.1016/S2214-109X(21)00208-4