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An optimal antitumor response by a novel CEA/CD3 bispecific antibody for colorectal cancers

BACKGROUND: CD3-based bispecific T cell engagers (bsTCEs) are one of the most promising bispecific antibodies for effective cancer treatments. To elicit target-specific T cell-mediated cytotoxicity, these bsTCEs contain at least one binding unit directed against a tumor antigen and another binding u...

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Detalles Bibliográficos
Autores principales:	Wang, Ninghai, Patel, Harshal, Schneider, Irene C, Kai, Xin, Varshney, Avanish K, Zhou, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Bispecific Antibody CMC
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220303/ https://www.ncbi.nlm.nih.gov/pubmed/34169228 http://dx.doi.org/10.1093/abt/tbab009

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