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The Plasmodium falciparum Rh5 invasion protein complex reveals an excess of rare variant mutations

BACKGROUND: The invasion of the red blood cells by Plasmodium falciparum merozoites involves the interplay of several proteins that are also targets for vaccine development. The proteins PfRh5-PfRipr-PfCyRPA-Pfp113 assemble into a complex at the apical end of the merozoite and are together essential...

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Detalles Bibliográficos
Autores principales: Ndwiga, Leonard, Osoti, Victor, Ochwedo, Kevin Omondi, Wamae, Kevin, Bejon, Philip, Rayner, Julian C., Githinji, George, Ochola-Oyier, Lynette Isabella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220363/
https://www.ncbi.nlm.nih.gov/pubmed/34162366
http://dx.doi.org/10.1186/s12936-021-03815-x