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The Plasmodium falciparum Rh5 invasion protein complex reveals an excess of rare variant mutations
BACKGROUND: The invasion of the red blood cells by Plasmodium falciparum merozoites involves the interplay of several proteins that are also targets for vaccine development. The proteins PfRh5-PfRipr-PfCyRPA-Pfp113 assemble into a complex at the apical end of the merozoite and are together essential...
Autores principales: | Ndwiga, Leonard, Osoti, Victor, Ochwedo, Kevin Omondi, Wamae, Kevin, Bejon, Philip, Rayner, Julian C., Githinji, George, Ochola-Oyier, Lynette Isabella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220363/ https://www.ncbi.nlm.nih.gov/pubmed/34162366 http://dx.doi.org/10.1186/s12936-021-03815-x |
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