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Metabolic imaging with hyperpolarized [1-(13)C] pyruvate in patient-derived preclinical mouse models of breast cancer

(13)C nuclear spin hyperpolarization can increase the sensitivity of detection in an MRI experiment by more than 10,000-fold. (13)C magnetic resonance spectroscopic imaging (MRSI) of hyperpolarized (13)C label exchange between injected [1-(13)C]pyruvate and the endogenous tumor lactate pool can be u...

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Detalles Bibliográficos
Autores principales:	Ros, Susana, Wright, Alan J., Bruna, Alejandra, Caldas, Carlos, Brindle, Kevin M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220404/ https://www.ncbi.nlm.nih.gov/pubmed/34189473 http://dx.doi.org/10.1016/j.xpro.2021.100608

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