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Multifunctional inhibitors of SARS-CoV-2 by MM/PBSA, essential dynamics, and molecular dynamic investigations

The ongoing COVID-19 pandemic demands a novel approach to combat and identify potential therapeutic targets. The SARS-CoV-2 infection causes a hyperimmune response followed by a spectrum of diseases. Limonoids are a class of triterpenoids known to prevent the release of IL-6, IL-15, IL-1α, IL-1β via...

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Detalles Bibliográficos
Autores principales:	Kumar, K. Amith, Sharma, Monica, Dalal, Vikram, Singh, Vishakha, Tomar, Shailly, Kumar, Pravindra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Inc. 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220440/ https://www.ncbi.nlm.nih.gov/pubmed/34237666 http://dx.doi.org/10.1016/j.jmgm.2021.107969

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