Bioinspired Nucleophilic Attack on a Tungsten-Bound Acetylene: Formation of Cationic Carbyne and Alkenyl Complexes

[Image: see text] Inspired by the proposed inner-sphere mechanism of the tungstoenzyme acetylene hydratase, we have designed tungsten acetylene complexes and investigated their reactivity. Here, we report the first intermolecular nucleophilic attack on a tungsten-bound acetylene (C(2)H(2)) in bioins...

Descripción completa

Detalles Bibliográficos
Autores principales: Ehweiner, Madeleine A., Peschel, Lydia M., Stix, Niklas, Ćorović, Miljan Z., Belaj, Ferdinand, Mösch-Zanetti, Nadia C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220502/
https://www.ncbi.nlm.nih.gov/pubmed/33852290
http://dx.doi.org/10.1021/acs.inorgchem.1c00643
Descripción
Sumario:[Image: see text] Inspired by the proposed inner-sphere mechanism of the tungstoenzyme acetylene hydratase, we have designed tungsten acetylene complexes and investigated their reactivity. Here, we report the first intermolecular nucleophilic attack on a tungsten-bound acetylene (C(2)H(2)) in bioinspired complexes employing 6-methylpyridine-2-thiolate ligands. By using PMe(3) as a nucleophile, we isolated cationic carbyne and alkenyl complexes.

Ejemplares similares