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Development and evaluation of a composite dosage form containing desmopressin acetate for buccal administration
Desmopressin acetate (DDAVP) is an oligopeptide indicated for the treatment of primary nocturnal enuresis, for example. The poor oral bioavailability of DDAVP accelerated a shift to alternative routes of administration like nasal and oromucosal, whereby nasal administration results in high fluctuati...
Autores principales: | Kottke, Dina, Burckhardt, Bjoern B., Knaab, Tanja C., Breitkreutz, Jörg, Fischer, Björn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220551/ https://www.ncbi.nlm.nih.gov/pubmed/34195604 http://dx.doi.org/10.1016/j.ijpx.2021.100082 |
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