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An increase in O-GlcNAcylation of Sp1 down-regulates the gene expression of pi class glutathione S-transferase in diabetic mice

Oxidative stress is a key factor contributing to the development of diabetes complications. Glutathione S-transferases (GSTs) protect against products of oxidative stress by conjugating glutathione to electrophilic substrates, producing compounds that are generally less reactive and more soluble. Th...

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Detalles Bibliográficos
Autores principales: Oliveri, Leda María, Buzaleh, Ana María, Gerez, Esther Noemí
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220555/
https://www.ncbi.nlm.nih.gov/pubmed/34195388
http://dx.doi.org/10.1016/j.bbrep.2021.101049