Alveolar epithelial cell fate is maintained in a spatially restricted manner to promote lung regeneration after acute injury

Alveolar epithelial type 2 (AT2) cells integrate signals from multiple molecular pathways to proliferate and differentiate to drive regeneration of the lung alveolus. Utilizing in vivo genetic and ex vivo organoid models, we investigated the role of Fgfr2 signaling in AT2 cells across the lifespan a...

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Detalles Bibliográficos
Autores principales: Liberti, Derek C., Kremp, Madison M., Liberti, William A., Penkala, Ian J., Li, Shanru, Zhou, Su, Morrisey, Edward E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220578/
https://www.ncbi.nlm.nih.gov/pubmed/33979629
http://dx.doi.org/10.1016/j.celrep.2021.109092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220578/
https://www.ncbi.nlm.nih.gov/pubmed/33979629
http://dx.doi.org/10.1016/j.celrep.2021.109092

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