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Well-differentiated liposarcoma of the cheek misdiagnosed for lipoma: A case report
INTRODUCTION: Liposarcoma is the most common sarcoma entity and accounts for 17% to 30% of soft tissue sarcomas. There are several histological types including well-differentiated liposarcoma. This paper aims to underline the interest of immunohistochemical and cytogenetic studies to diagnose well-d...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220591/ https://www.ncbi.nlm.nih.gov/pubmed/34153693 http://dx.doi.org/10.1016/j.ijscr.2021.106116 |
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author | IRO, Salissou Maadane, Amina Hassani, Fatema Ez-zahrae Azami Raiteb, Mohamed Kerdoud, Ouassime Slimani, Faiçal |
author_facet | IRO, Salissou Maadane, Amina Hassani, Fatema Ez-zahrae Azami Raiteb, Mohamed Kerdoud, Ouassime Slimani, Faiçal |
author_sort | IRO, Salissou |
collection | PubMed |
description | INTRODUCTION: Liposarcoma is the most common sarcoma entity and accounts for 17% to 30% of soft tissue sarcomas. There are several histological types including well-differentiated liposarcoma. This paper aims to underline the interest of immunohistochemical and cytogenetic studies to diagnose well-differentiated liposarcoma and to show the delicacy of performing a surgical procedure in the cheek area. CASE PRESENTATION: The authors report the case of a 48-year-old female patient who presented with the recurrence of a right jugal mass initially diagnosed as a lipoma on the resection specimen. The patient was reoperated 5 years later and further immunohistochemical and cytogenetic studies confirmed the diagnosis of well-differentiated jugal liposarcoma. DISCUSSION: Sarcomas are rare malignant tumors of mesenchymal origin, arising from connective and supporting tissues. It should be noted that certain MRI features can distinguish liposarcoma from lipoma. Conventional histology and immunohistochemistry are the basic means for the diagnosis and classification of liposarcomas. However, molecular biology can add to the pathologist's analysis and rule out differential diagnoses Liposarcoma of the maxillofacial region has a better prognosis compared to other parts of the human body. CONCLUSION: This paper underlines the interest of complementary immunohistochemical and cytogenetic studies to differentiate well-differentiated liposarcoma from lipoma as well as the potential for local recurrence of liposarcomas. |
format | Online Article Text |
id | pubmed-8220591 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-82205912021-06-29 Well-differentiated liposarcoma of the cheek misdiagnosed for lipoma: A case report IRO, Salissou Maadane, Amina Hassani, Fatema Ez-zahrae Azami Raiteb, Mohamed Kerdoud, Ouassime Slimani, Faiçal Int J Surg Case Rep Case Report INTRODUCTION: Liposarcoma is the most common sarcoma entity and accounts for 17% to 30% of soft tissue sarcomas. There are several histological types including well-differentiated liposarcoma. This paper aims to underline the interest of immunohistochemical and cytogenetic studies to diagnose well-differentiated liposarcoma and to show the delicacy of performing a surgical procedure in the cheek area. CASE PRESENTATION: The authors report the case of a 48-year-old female patient who presented with the recurrence of a right jugal mass initially diagnosed as a lipoma on the resection specimen. The patient was reoperated 5 years later and further immunohistochemical and cytogenetic studies confirmed the diagnosis of well-differentiated jugal liposarcoma. DISCUSSION: Sarcomas are rare malignant tumors of mesenchymal origin, arising from connective and supporting tissues. It should be noted that certain MRI features can distinguish liposarcoma from lipoma. Conventional histology and immunohistochemistry are the basic means for the diagnosis and classification of liposarcomas. However, molecular biology can add to the pathologist's analysis and rule out differential diagnoses Liposarcoma of the maxillofacial region has a better prognosis compared to other parts of the human body. CONCLUSION: This paper underlines the interest of complementary immunohistochemical and cytogenetic studies to differentiate well-differentiated liposarcoma from lipoma as well as the potential for local recurrence of liposarcomas. Elsevier 2021-06-16 /pmc/articles/PMC8220591/ /pubmed/34153693 http://dx.doi.org/10.1016/j.ijscr.2021.106116 Text en © 2021 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report IRO, Salissou Maadane, Amina Hassani, Fatema Ez-zahrae Azami Raiteb, Mohamed Kerdoud, Ouassime Slimani, Faiçal Well-differentiated liposarcoma of the cheek misdiagnosed for lipoma: A case report |
title | Well-differentiated liposarcoma of the cheek misdiagnosed for lipoma: A case report |
title_full | Well-differentiated liposarcoma of the cheek misdiagnosed for lipoma: A case report |
title_fullStr | Well-differentiated liposarcoma of the cheek misdiagnosed for lipoma: A case report |
title_full_unstemmed | Well-differentiated liposarcoma of the cheek misdiagnosed for lipoma: A case report |
title_short | Well-differentiated liposarcoma of the cheek misdiagnosed for lipoma: A case report |
title_sort | well-differentiated liposarcoma of the cheek misdiagnosed for lipoma: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220591/ https://www.ncbi.nlm.nih.gov/pubmed/34153693 http://dx.doi.org/10.1016/j.ijscr.2021.106116 |
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